Sparteine | CAS No. 90-39-1

Sparteine

Basic Information

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CAS Number

90-39-1

Molecular Formula

C15H26N2

Molecular Weight

234.39 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

30.5°C

Boiling Point

147°C/3.5mmHg

Density

1.02

Flash Point

113 ºC

Refractive Index

1.528

Specific Rotation

D21 -16.4° (c = 10 in abs alc)

SMILES

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C1CCC2N(C1)CC1CC2CN2C1CCCC2

InChI

InChI=1S/C15H26N2/c1-3-7-16-11-13-9-12(14(16)5-1)10-17-8-4-2-6-15(13)17/h12-15H,1-11H2/t12-,13-,14-,15+/m0/s1

InChIKey

SLRCCWJSBJZJBV-ZQDZILKHSA-N

LogP

2.3451000000000004

pKa

2.24, 9.46(at 20℃)

Topological Polar Surface Area

6.48 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

263

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class 6.1(b) Class 6.1(b)

Sensitiveness

Sensitive to air

Synonyms & References

English

Sparteine
L-(-)-SPARTEINE
(-)-LUPINIDINE
LUPINIDINE
(-)-spartein
6-beta,7-alpha,9-alpha,11-alpha-pachycarpine
6beta,7alpha,9alpha,11alpha-Pachycarpine
(-)-Sparteine
(+)-SPARTEINE
(-)-sordarin
(-)-Lupinidine
Lupinidine
(7S,7aR,14S,14aS)-Dodecahydro-7,14-methano-2H,6H-dipyrido[1,2-a:1′,2′-e][1,5]diazocine (ACI)
7,14-Methano-2H,6H-dipyrido[1,2-a:1′,2′-e][1,5]diazocine, dodecahydro-, [7S-(7α,7aα,14α,14aβ)]- (ZCI)
Sparteine (6CI, 8CI)
6β,7α,9α,11α-Pachycarpine
L-(-)-Sparteine
L-Sparteine
l-Sparteine
Lupinidin
MeSH ID: D013034
Spartein

MDL Number

MFCD00069653

Customs Code

2933990090

FAQ

What are the physical and chemical properties of Sparteine (CAS: 90-39-1)?

Sparteine (CAS: 90-39-1) is a white crystalline powder. It has a molecular weight of approximately 201.28 g/mol and is slightly soluble in water but more soluble in organic solvents. Chemically, sparteine is highly reactive towards bases and can undergo alkaline hydrolysis. It does not react with acids or oxidizing agents under normal conditions.

How is Sparteine (CAS: 90-39-1) typically synthesized?

Sparteine (CAS: 90-39-1) can be synthesized through the reduction of sparteine hydrochloride using lithium aluminum hydride (LAH) as a reducing agent. The synthesis involves the use of a solvent such as ethanol and typically requires anhydrous conditions to prevent unwanted reactions. The product is then isolated by filtration and recrystallization to obtain the desired crystalline form.

What industries use Sparteine (CAS: 90-39-1)?

Sparteine (CAS: 90-39-1) is primarily used in the pharmaceutical industry as an antispasmodic and in veterinary medicine. It has also shown potential in the development of certain types of sensors for detecting biological and chemical agents. Its use in other industries such as polymers and semiconductors is limited due to its specific chemical properties and toxicity.

What precautions should be taken when handling Sparteine (CAS: 90-39-1)?

When handling sparteine (CAS: 90-39-1), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. Sparteine should be handled in a fume hood to minimize exposure. In case of a spill, it is crucial to clean it up immediately using appropriate materials and to follow the safety data sheet (SDS) guidelines for proper disposal. Sparteine is toxic and can cause irritation to the skin and eyes, so immediate medical attention should be sought if exposure occurs.