2-Methoxyphenol

Basic Information

View in Editor

CAS Number

90-05-1

Molecular Formula

C7H8O2

Molecular Weight

124.14 g/mol

EINECS

201-964-7

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

Physical State

Clear colorless to light yellow

Melting Point

26-29 °C

Boiling Point

205 °C

Density

1.129 g/mL at 25 °C

Water Solubility

17 g/L (15 ºC)

Flash Point

180 °F

Solubility

H2O: insoluble

Refractive Index

n20/D 1.543(lit.)

Vapor Pressure

0.11 mm Hg ( 25 °C)

Vapor Density

4.27 (vs air)

Odor

at 1.00 % in dipropylene glycol. phenolic smoke spice vanilla woody

Odor Threshold

0.0074ppm

SMILES

View in Editor

COc1ccccc1O

InChI

InChI=1S/C7H8O2/c1-9-7-5-3-2-4-6(7)8/h2-5,8H,1H3

InChIKey

LHGVFZTZFXWLCP-UHFFFAOYSA-N

LogP

1.4008

pKa

9.98(at 25℃)

Topological Polar Surface Area

29.46 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

Safety Information

View Safety Information

GHS Hazard Pictograms

H302

H315

H319

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Hazard Class

Class 6.1(b) Class 6.1(b)

Storage Conditions

2-8℃

Stability

Stable, but air and light sensitive. Combustible. Incompatible with strong oxidizing agents.

Sensitiveness

Air Sensitive

Auto-ignition Temperature

750 °C

Toxicity

LD50 orally in rats: 725 mg/kg (Taylor)

Synonyms & References

English

PYROCATECHOL MONOMETHYL ETHER
PYROGUAIAC ACID
O-METHOXYPHENOL
O-METHYLCATECHOL
O-HYDROXYANISOLE
CATECHOL MONOMETHYL ETHER
Gulaiacol
GUAJACOL
2-Methoxyphenol
GAIACOL
o-Methoxyphenol
o-Hydroxyanisole
Catechol monomethyl ether
Guaiaco
1-Hydroxy-2-methoxybenzene
a-methoxyphenolsalicyl methyl ether
Guaiacol
Guaiacol 1,2-methoxy-Phenol o-methoxy-pheno
1-Hydroxy-2-Methoxybenzene
2-Hydroxyanisole
Pyrocatechol Monomethyl Ether
愈创木酚
Phenol, 2-methoxy-
Methylcatechol
Guaiastil
Guaicol
Pyroguaiac acid
o-Guaiacol
Guaicolina
Guajol
Guasol

MDL Number

MFCD00002185

EC Number

201-964-7

Customs Code

29095010

FAQ

What is 2-Methoxyphenol (CAS: 90-05-1)?

2-Methoxyphenol, also known as 2-methoxyphenol, is a phenolic compound with the chemical formula C7H8O2. It is a colorless to yellowish liquid, slightly soluble in water, and has a characteristic aromatic odor. Commonly used as a fragrance ingredient and antioxidant, it exhibits mild acidity due to the hydroxyl group. CAS 90-05-1 identifies this compound uniquely, which is found in natural sources like certain plants and synthesized for industrial applications.

What are the main uses of 2-Methoxyphenol (CAS: 90-05-1)?

2-Methoxyphenol (CAS 90-05-1) is widely used in pharmaceuticals as a precursor for drug synthesis, in the food industry as a flavoring agent, and in industrial applications as a solvent or stabilizer. It also serves as a key component in perfumes and cosmetics due to its aromatic properties. In research, it is studied for its antioxidant activity and potential applications in organic chemistry. Its versatility makes it valuable across multiple sectors, including fragrance and pharmaceutical development.

Is 2-Methoxyphenol (CAS: 90-05-1) safe?

2-Methoxyphenol (CAS 90-05-1) is generally safe in low concentrations but requires caution during handling. It may cause skin and eye irritation, and inhalation or ingestion can be harmful. Safety standards recommend using protective gear like gloves and goggles, and adhering to OSHA guidelines for exposure limits. Proper storage and ventilation are essential to minimize risks, ensuring safe use in laboratories and industrial settings.

How should 2-Methoxyphenol (CAS: 90-05-1) be stored?

2-Methoxyphenol (CAS 90-05-1) should be stored in a sealed, light-resistant container in a cool, dry place, away from heat and direct sunlight. Maintain low humidity to prevent degradation, and ensure it is kept in a well-ventilated area. Avoid exposure to air to maintain stability, as it is sensitive to oxidation. Store according to safety data sheets (SDS) guidelines to preserve its chemical integrity and ensure safe handling.