Tazobactam sodium

Basic Information

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CAS Number

89785-84-2

Molecular Formula

C10H11N4NaO5S

Molecular Weight

322.27 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

140-147°C

Boiling Point

707.1°C at 760 mmHg

Water Solubility

Soluble in water.Soluble in water and methanol.

Flash Point

>110°(230°F)

Solubility

H2O: 50 mg/mL, clear, colorless

Refractive Index

1.82

SMILES

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CC1(C(N2C(S1(=O)=O)CC2=O)C(=O)[O-])CN3C=CN=N3.[Na+]

InChI

1S/C10H12N4O5S.Na/c1-10(5-13-3-2-11-12-13)8(9(16)17)14-6(15)4-7(14)20(10,18)19;/h2-3,7-8H,4-5H2,1H3,(H,16,17);/t7-,8+,10+;/m1./s1

InChIKey

ZUNWFYFXHGWFRA-QVUDESDKSA-N

LogP

-1.83920

Complexity

579

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

[2s-(2a,3b,5a)]-3-methyl-7-oxo-3(1h,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide sodium salt
[2S-(2ALPHA, 3BETA, 5ALPHA)]-3-METHYL-7-OXO-3(1H,2,3-TRIAZOL-1-YLMETHYL)-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLIC ACID 4,4-DIOXIDE SODIUM SALT
CL-298741 SODIUM SALT
TAZOBACTAM SODIUM
TAZOBACTAM SODIUM SALT
YTR-830H SODIUM SALT
2-alpha-methyl-2-beta-(1,2,3-triazol-1-ylmethyl)penam-3-alpha-carboxylicacid
3-methyl-7-oxo-3-(1h-1,2,3-triazol-1-ylmethyl)-,4,4-dioxide,sodiumsalt,(2s-(2-alpha,3-beta,5-alp4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylicaci
4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylicacid,3-methyl-7-oxo-3-(1h-1,2,3
cl307579
-triazol-1-ylmethyl)-,4,4-dioxide,sodiumsalt,(2s-(2-alpha,3-beta,5-alpha))
ytr830
(2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid 4,4-dioxide Sodium Salt
CL-30757
[2s-(2α,3β,5α)]-3-methyl-7-oxo-3(1h,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide
Piperacillin sodium salt
PHARMA-0692
Tazobactam Sodium Sa
SODIUM
TAZOBACTAMACID
1H-1,2,3-Triazole, 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid deriv. (ZCI)
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, sodium salt, (2S,3S,5R)- (9CI)
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-, 4,4-dioxide, sodium salt, [2S-(2α,3β,5α)]- (ZCI)
CL 307579
Tazobactam sodium
YTR 830
Tazobactam (as sodium)
CHEBI:85192
CAS-89785-84-2
Sodium (2S,3S,5R)-3-methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate, 4,4-dioxide
tazobactum

MDL Number

MFCD00917472

Customs Code

2934999090

FAQ

What is Tazobactam sodium (CAS: 89785-84-2)?

Tazobactam sodium is a β-lactamase inhibitor used in combination with β-lactam antibiotics to enhance their effectiveness against certain resistant bacteria. It has the molecular formula C12H14N2NaO5S and is colorless to slightly yellowish-white crystals or crystalline powder.

What are the main uses of Tazobactam sodium (CAS: 89785-84-2)?

Tazobactam sodium is primarily used as a component in combination antibiotics, such as Tazobactam/Sulbactam, to treat infections caused by β-lactamase-producing bacteria. It is used in the treatment of respiratory, urinary, and other infections.

Is Tazobactam sodium (CAS: 89785-84-2) safe?

Tazobactam sodium, when used as directed, is generally considered safe. However, it may cause allergic reactions and gastrointestinal side effects. Proper handling and storage are essential to avoid inhalation and skin contact. Always follow recommended safety guidelines and consult a healthcare provider if any adverse effects occur.

How should Tazobactam sodium (CAS: 89785-84-2) be stored?

Tazobactam sodium should be stored in well-closed, light-resistant, and moisture-proof containers at a temperature not exceeding 25°C. Keep it away from heat, direct sunlight, and sources of ignition. Protect from humidity. Do not store in the presence of strong acids or reducing agents.