Bicyclo[3.1.0]hexan-3-amine hydrochloride | CAS No. 89676-80-2

Bicyclo[3.1.0]hexan-3-amine hydrochloride

Basic Information

CAS Number

89676-80-2

Molecular Formula

C6H12ClN

Molecular Weight

133.62 g/mol

AD

Basic Physical Properties

C1C2C1CC(C2)N.Cl

InChI

InChI=1S/C6H11N.ClH/c7-6-2-4-1-5(4)3-6;/h4-6H,1-3,7H2;1H

InChIKey

WNIYKDGVQDRFKU-UHFFFAOYSA-N

LogP

1.1654

Topological Polar Surface Area

26.02 Ų

Hydrogen Bond Donor/Acceptor

2 / 1

Complexity

80.2

Synonyms & References

English

  • Bicyclo[3.1.0]hexan-3-amine hydrochloride
  • Bicyclo[3.1.0]hexan-3-amine, hydrochloride (7CI)
  • bicyclo[3.1.0]hexan-3-amine hydrochloride
  • Bicyclo[3.1.0]hexan-3-amine HCl
  • 89676-80-2
  • Bicyclo[3.1.0]hexan-3-aminehydrochloride
  • 79531-79-6
  • DB-197872
  • SB13252
  • AS-34205
  • CS-0049781
  • SB15849
  • bicyclo[3.1.0]hexan-3-amine;hydrochloride
  • SCHEMBL1583874
  • EN300-257512
  • AKOS024462847
  • MFCD27987290

MDL Number

MFCD27987290

FAQ

What are the physical and chemical properties of Bicyclo[3.1.0]hexan-3-amine hydrochloride (CAS: 89676-80-2)?

Bicyclo[3.1.0]hexan-3-amine hydrochloride is a white crystalline solid with a molecular weight of approximately 172.67 g/mol. It has a pKa of about 9.2 and is soluble in water and ethanol. It is less reactive than primary amines but can undergo typical amine reactions such as alkylation and acylation. The compound is stable under normal conditions but should be stored in a cool, dark place to prevent degradation.

How is Bicyclo[3.1.0]hexan-3-amine hydrochloride (CAS: 89676-80-2) typically synthesized?

Bicyclo[3.1.0]hexan-3-amine hydrochloride can be synthesized via the reaction of 3-hydroxymethylcyclohexane with hydrochloric acid. The process involves adding hydrochloric acid to a solution of 3-hydroxymethylcyclohexane under controlled conditions to promote the protonation and subsequent formation of the hydrochloride salt. The reaction is typically carried out at room temperature and under an inert atmosphere to enhance yield and purity.

What industries use Bicyclo[3.1.0]hexan-3-amine hydrochloride (CAS: 89676-80-2)?

Bicyclo[3.1.0]hexan-3-amine hydrochloride is primarily used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the polymer industry for its amine functionality, which can promote cross-linking and improve material properties. Additionally, it has applications in the semiconductor and sensor industries due to its ability to act as a precursor for functional materials.

What precautions should be taken when handling Bicyclo[3.1.0]hexan-3-amine hydrochloride (CAS: 89676-80-2)?

When handling Bicyclo[3.1.0]hexan-3-amine hydrochloride, it is important to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be stored in a cool, dry place and handled in a fume hood to avoid inhalation. In case of a spill, it should be cleaned up using appropriate absorbent materials, and the area should be ventilated. For detailed safety information, refer to the Safety Data Sheet (SDS).

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