Boc-N-methyl-D-leucine

Basic Information

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CAS Number

89536-84-5

Molecular Formula

C12H23NO4

Molecular Weight

245.32 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

62-66°C

Boiling Point

338.2°C at 760 mmHg

Density

1.053

Flash Point

158.3°C

Refractive Index

1.466

Specific Rotation

36±2°, c = 1% in DCM

SMILES

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CC(C)CC(C(=O)O)N(C)C(=O)OC(C)(C)C

InChI

InChI=1S/C12H23NO4/c1-8(2)7-9(10(14)15)13(6)11(16)17-12(3,4)5/h8-9H,7H2,1-6H3,(H,14,15)/t9-/m1/s1

InChIKey

YXJFAOXATCRIKU-SECBINFHSA-N

LogP

2.3526000000000007

Topological Polar Surface Area

66.84 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

281

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Boc-N-methyl-D-leucine
Boc-N-Me-D-Leu-OH
N-(tert-Butyloxycarbonyl)-N-methyl-D-leucine
Boc-D-MeLeu-OH
Boc-Nalpha-methyl-D-leucine
BOC-NΑ-METHYL-D-LEUCINE
BOC-D-ALA(TBU)-OH
BOC-D-LEU(ME)-OH
BOC-D-NEOPENTYLGLYCINE
BOC-D-NEOPENTYLGLY-OH
BOC-T-BUTYL-D-ALANINE
D-N-Boc-N-methylleucine
N-Boc-N-methyl-D-leucine
N-methyl-Boc-D-leucine
N-tert-butoxycarbonyl-N-methyl-D-leucine
N-[(1,1-Dimethylethoxy)carbonyl]-N-methyl-D-leucine (ACI)
(2R)-2-[[(tert-Butoxy)carbonyl](methyl)amino]-4-methylpentanoic acid
(2R)-4-Methyl-2-[methyl-[(2-methylpropan-2-yl)oxycarbonyl]amino]pentanoic acid
N-(tert-Butoxycarbonyl)-N-methyl-D-leucine
AKOS015836739
89536-84-5
YXJFAOXATCRIKU-SECBINFHSA-N
PD196691
(R)-2-(tert-butoxycarbonyl(methyl)amino)-4-methylpentanoic acid
HY-W009535
(2R)-2-{[(tert-butoxy)carbonyl](methyl)amino}-4-methylpentanoic acid
(2R)-2-[(tert-butoxycarbonyl)(methyl)amino]-4-methylpentanoic acid
FD21926
SCHEMBL69223
(R)-2-((tert-Butoxycarbonyl)(methyl)amino)-4-methylpentanoic acid
AS-19330

MDL Number

MFCD00076953

Customs Code

2922509090

FAQ

What is Boc-N-methyl-D-leucine (CAS: 89536-84-5)?

Boc-N-methyl-D-leucine is a protected amino acid derivative, commonly used in peptide synthesis and medicinal chemistry. Its chemical formula is C12H21NO3. It features a tert-butyloxycarbonyl (Boc) protecting group attached to the N-terminal of D-leucine with a methyl substitution on the side chain.

What are the main uses of Boc-N-methyl-D-leucine (CAS: 89536-84-5)?

Boc-N-methyl-D-leucine is primarily used in the synthesis of peptides and proteins, serving as a building block in solid-phase peptide synthesis. It is also explored in pharmaceutical research for drug development and as a component in certain therapeutic formulations.

Is Boc-N-methyl-D-leucine (CAS: 89536-84-5) safe?

Boc-N-methyl-D-leucine is generally safe when handled properly. However, it should be used with caution, as it may cause irritation to the skin and eyes. Protective measures include wearing gloves, goggles, and a lab coat. It is also advisable to work in a well-ventilated area or a fume hood.

How should Boc-N-methyl-D-leucine (CAS: 89536-84-5) be stored?

Boc-N-methyl-D-leucine should be stored in a cool, dry place away from direct sunlight and heat sources. It is recommended to keep it in a tightly sealed container, preferably a glass jar or a metal container, to protect it from moisture and light exposure. The ideal temperature range is between 15-25°C (59-77°F).