(1H-Indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone

Basic Information

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CAS Number

895152-66-6

Molecular Formula

C16H19NO

Molecular Weight

241.33 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

SMILES

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CC1(C(C1(C)C)C(=O)C2=CNC3=CC=CC=C32)C

InChI

InChI=1S/C16H19NO/c1-15(2)14(16(15,3)4)13(18)11-9-17-12-8-6-5-7-10(11)12/h5-9,14,17H,1-4H3

InChIKey

WYZQBEQQQKCTHM-UHFFFAOYSA-N

LogP

4.032800000000003

Topological Polar Surface Area

32.86 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

357

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H317 May cause an allergic skin reaction
Sensitization, Skin

Synonyms & References

English

(1H-Indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone
WYZQBEQQQKCTHM-UHFFFAOYSA-N
4824AC
SEL11352432
AX8229380
ST24020101
J3.625.289H
1H-indol-3-yl(2,2,3,3-tetramethylcyclopropyl)methanone
3-(2,2,3,3-tetramethylcyclopropanecarbonyl)-1H-indole
(1H-indol-3-yl)(2,2,3,3-tetramethyl cyclopropyl)methanone
1H-Indol-3-yl(2,2,3,3-tetramethylcyclopropyl)methanone (ACI)
1H-indol-3-yl-(2,2,3,3-tetramethylcyclopropyl)methanone
AKOS015151113
DTXCID90597954
PD018452
DB-088388
DP-UR-144
NS00018398
(1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone
CS-0089100
UNII-674PB4BFT4
Despentyl-UR-144
895152-66-6
DS-16655
SCHEMBL2079145
674PB4BFT4
MFCD13689217
DTXSID10647203
Methanone, 1H-indol-3-yl(2,2,3,3-tetramethylcyclopropyl)-
CHEBI:170056

MDL Number

MFCD13689217

FAQ

What are the physical and chemical properties of (1H-Indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone (CAS: 895152-66-6)?

(1H-Indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone is a crystalline solid with a molecular weight of approximately 248.34 g/mol. It has limited water solubility and is soluble in organic solvents like dichloromethane and acetone. The compound is relatively stable under normal conditions but may react with strong bases or oxidizing agents. It is important to handle it in a well-ventilated area and wear appropriate personal protective equipment.

How is (1H-Indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone (CAS: 895152-66-6) typically synthesized?

(1H-Indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone is typically synthesized through a multistep process involving the coupling of indole and 2,2,3,3-tetramethylcyclopropyl methanol. The reaction often uses a suitable base and is conducted under mild conditions. The yield and selectivity can be optimized with the appropriate choice of catalysts and solvents.

What industries use (1H-Indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone (CAS: 895152-66-6)?

(1H-Indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone finds applications in pharmaceuticals, where it serves as a precursor for synthesizing complex organic molecules. It may also be used in the preparation of certain polymers and in the development of sensors for detecting specific chemicals.

What precautions should be taken when handling (1H-Indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone (CAS: 895152-66-6)?

When handling (1H-Indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone, it is crucial to wear appropriate personal protective equipment, including gloves, goggles, and a lab coat. Conduct the operations in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate methods and materials. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.