D-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-NLE-NH2 | CAS No. 89430-34-2

D-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-NLE-NH2

Basic Information

CAS Number

89430-34-2

Molecular Formula

C58H77N13O10

Molecular Weight

1116.31 g/mol

AD

Basic Physical Properties

CCCCC(C(=O)N)NC(=O)C(CC(C)C)NC(=O)C(CC1=CNC2=CC=CC=C21)NC(=O)C(CC3=CC=CC=C3)NC(=O)C(CC4=CNC5=CC=CC=C54)NC(=O)C(CCC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C6CCCN6

InChI

InChI=1S/C58H77N13O10/c1-4-5-18-41(51(61)74)65-55(78)45(27-33(2)3)68-57(80)48(30-36-32-64-40-20-12-10-17-38(36)40)71-56(79)46(28-34-14-7-6-8-15-34)69-58(81)47(29-35-31-63-39-19-11-9-16-37(35)39)70-54(77)44(23-25-50(60)73)67-53(76)43(22-24-49(59)72)66-52(75)42-21-13-26-62-42/h6-12,14-17,19-20,31-33,41-48,62-64H,4-5,13,18,21-30H2,1-3H3,(H2,59,72)(H2,60,73)(H2,61,74)(H,65,78)(H,66,75)(H,67,76)(H,68,80)(H,69,81)(H,70,77)(H,71,79)

InChIKey

OFDJVNRFKDPBKR-UHFFFAOYSA-N

LogP

1.0753000000000075

Topological Polar Surface Area

376.5799999999998 Ų

Hydrogen Bond Donor/Acceptor

16 / 23

Complexity

2160

Synonyms & References

English

  • L-Norleucinamide,D-prolyl-L-glutaminyl-L-glutaminyl-D-tryptophyl-L-phenylalanyl-D-tryptophyl-L-leucyl-(9CI)
  • (D-PRO4,D-TRP7,9,NLE11)-SUBSTANCE P (4-11)
  • (D-Pro4,D-Trp7·9,Nle11)-Substance P (4-11)
  • [D-Pro4,D-Trp7,9,Nle11]-Substance P (4-11)
  • (D-pro4,D-trp7,9,nle11)-substance P*fragment 4-11
  • 4-Pro-7,9-Trp-11-nle-substance p (4-11)
  • D-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-NLE-NH2
  • D-Pro-L-Gln-L-Gln-D-Trp-L-Phe-D-Trp-L-Leu-L-Nle-NH2
  • H-D-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-NLE-NH2
  • Pttnl-sp(4-11)
  • substance P (4-11),Pro(4)-Trp(7,9)-Nle(11)
  • SUBSTANCE P [D-PRO4,D-TRP7,9,NLE11]-FRAGMENT 4-11
  • Substance P,fragment 4-11,[D-Pro4,D-Trp7,9,Nle11]
  • N-[5-amino-1-[[1-[[1-[[1-[[1-[(1-amino-1-oxohexan-2-yl)amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1,5-dioxopentan-2-yl]-2-(pyrrolidine-2-carbonylamino)pentanediamide

MDL Number

MFCD00133834

FAQ

What regulatory guidelines apply to D-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Nle-NH2 (CAS: 89430-34-2)?

D-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Nle-NH2 (CAS: 89430-34-2) falls under the purview of several regulatory guidelines. For industrial and environmental safety, it adheres to the GHS classification system. In terms of production and import, it must comply with REACH regulations. Additionally, the FDA and EPA have specific requirements for its use in research and medical applications, focusing on safety and environmental impact assessments.

Are there alternatives to D-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Nle-NH2 (CAS: 89430-34-2) in synthesis?

When synthesizing D-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Nle-NH2 (CAS: 89430-34-2), chemists often consider using isomers or analogs such as D-Pro-Gln-D-Trp-Phe-D-Trp-Leu-Nle-NH2 or D-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Nle-NH2. Other alternatives include using different amino acids or modifying the sequence to create similar compounds with similar functional properties.

What is the market or research trend for D-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Nle-NH2 (CAS: 89430-34-2)?

The market for D-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Nle-NH2 (CAS: 89430-34-2) is primarily driven by its use in research for biochemistry and pharmaceuticals. Recent trends indicate growing interest in its potential applications in drug discovery and personalized medicine. Research is focusing on its biological activity and therapeutic potential, with a particular emphasis on its role in protein synthesis and metabolism.

How should waste containing D-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Nle-NH2 (CAS: 89430-34-2) be handled?

Waste containing D-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Nle-NH2 (CAS: 89430-34-2) should be collected in appropriate containers and stored under controlled conditions to prevent contamination. Proper incineration or professional waste disposal services should be used to ensure compliance with environmental regulations. Handling should be done with protective gear and in a well-ventilated area to minimize exposure and environmental impact.

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