5-Chloro-2,3-difluoropyridine

Basic Information

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CAS Number

89402-43-7

Molecular Formula

C5H2ClF2N

Molecular Weight

149.53 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

47-49 C

Boiling Point

135°C

Density

1.442 g/mL at 25 °C

Refractive Index

1.4720-1.4760

SMILES

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C1=C(C=NC(=C1F)F)Cl

InChI

InChI=1S/C5H2ClF2N/c6-3-1-4(7)5(8)9-2-3/h1-2H

InChIKey

PERMDYZFNQIKBL-UHFFFAOYSA-N

LogP

2.0132

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

101

Safety Information

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GHS Hazard Pictograms

H226

H302

H412

Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

H302 Harmful if swallowed
Acute toxicity, oral

H412 Harmful to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard

Hazard Class

Class 3 Class 3

Synonyms & References

English

5-Chloro-2,3-difluoropyridine
2,3-DIFLUORO-5-CHLOROPYRIDIN
2,3-DIFLUORO-5-CHLOROPYRIDINE
2,3-Difluoro-5-Chloro
2,3-Difulor-5-Chloropyridine
2,3-DICHLORO-5-FLUORO PYRIDINE
4-Nitrobenzyl chloride
Pyridine,5-chloro-2,3-difluoro-
3-Chloro-5,6-difluoropyridine
5-CHLORO-2,3-DIFLUOROPYRIDINE
5-Chloro-2,3-Difluoropyridine96%
intermediate for Clodinafop-propargyl
5-Chloro-2,3-difluoropyridine 98%
5-Chloro-2,3-difluoropyridine (ACI)
2,3-Difluoro-5-chloropyridine
589402-43-7
MFCD04039314
2,3-DIFLUORO-5-CHLORO PYRIDINE
NS00005305
DTXSID001008801
AC-8181
5-chloro-2,3-difluoro-pyridine
CS-W003144
2,3-Difluoro-5-chloropyridine, 95%
DB-292156
EN300-98067
89402-43-7
UNII-NTR2GM7GHF
AC-23446
Z1255442949
Pyridine, 5-chloro-2,3-difluoro-

MDL Number

MFCD04039314

Customs Code

2933399090

FAQ

What is 5-Chloro-2,3-difluoropyridine (CAS: 89402-43-7)?

5-Chloro-2,3-difluoropyridine (CAS: 89402-43-7) is a halogenated pyridine derivative with the chemical formula C5H3ClF2N. It features a six-membered aromatic ring with chlorine and fluorine substituents at positions 5, 2, and 3, respectively. This compound is typically a colorless solid with moderate solubility in organic solvents and exhibits stability under standard conditions. Its reactivity and functional groups make it a valuable intermediate in organic synthesis.

What are the main uses of 5-Chloro-2,3-difluoropyridine (CAS: 89402-43-7)?

5-Chloro-2,3-difluoropyridine (CAS: 89402-43-7) is primarily used in pharmaceutical research as a building block for drug development, particularly in compounds targeting metabolic disorders. It also serves industrial applications in agrochemicals and materials science, and is utilized in research for synthesizing fluorinated aromatic derivatives. Its unique structure supports diverse chemical transformations, making it essential in organic chemistry and chemical innovation.

Is 5-Chloro-2,3-difluoropyridine (CAS: 89402-43-7) safe?

5-Chloro-2,3-difluoropyridine (CAS: 89402-43-7) requires careful handling due to its potential toxicity. It may irritate the skin, eyes, and respiratory system, and prolonged exposure could pose health risks. Safety standards recommend wearing protective gloves, goggles, and lab coats, and working in a well-ventilated area. Always follow OSHA guidelines and proper chemical safety protocols when handling this compound.

How should 5-Chloro-2,3-difluoropyridine (CAS: 89402-43-7) be stored?

5-Chloro-2,3-difluoropyridine (CAS: 89402-43-7) should be stored in a tightly sealed container in a cool, dry, and dark location. It is stable at room temperature but should be protected from moisture and light to prevent degradation. Keep away from strong oxidizers and incompatible substances. Store in a well-ventilated area to ensure safety and maintain chemical integrity.