Salmeterol | CAS No. 89365-50-4

Salmeterol

Basic Information

View in Editor

CAS Number

89365-50-4

Molecular Formula

C25H37NO4

Molecular Weight

415.57 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

Melting Point

75-77°C

Boiling Point

603°C at 760 mmHg

SMILES

View in Editor

C1=CC=C(C=C1)CCCCOCCCCCCNCC(C2=CC(=C(C=C2)O)CO)O

InChI

InChI=1S/C25H37NO4/c27-20-23-18-22(13-14-24(23)28)25(29)19-26-15-7-1-2-8-16-30-17-9-6-12-21-10-4-3-5-11-21/h3-5,10-11,13-14,18,25-29H,1-2,6-9,12,15-17,19-20H2

InChIKey

GIIZNNXWQWCKIB-UHFFFAOYSA-N

LogP

4.107400000000004

Topological Polar Surface Area

81.95 Å²

Hydrogen Bond Donor/Acceptor

4 / 5

Complexity

403

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Salmeterol
4-HYDROXY-A1-[[[6-(4-PHENYLBUTOXY)HEXYL]AMINO]METHYL]-1,3-BENZENEDIMETHANOL
2-(hydroxymethyl)-4-[1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino] ethyl]-phenol
(+-)-4-hydroxy-alpha1-(((6-(4-phenylbutoxy)hexyl)amino)methyl)-1,3-benzenedi
1,3-benzenedimethanol,4-hydroxy-alpha1-(((6-(4-phenylbutoxy)hexyl)amino)methyl
gr33343x
SalmeterolXenofoate
4-Hydroxy-3-[hydroxymethyl]phenyl-N-[6-phenylbutoxyhexyl]ethanolamine
Salmeterol See S090100
2-hydroxymethyl-4-{1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl}phenol
SALMETEROL(SUBJECTTOPATENTFREE)
SAMETEROL
serevent (R)
SalMeterol iMpurity
Serevent
Aeromax
Astmerole
Salmeterolum [Latin]
GR 33343X
SALMATEROL
2-(hydroxymethyl)-4-[1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl]phenol
SN408D
2-(hydroxymethyl)-4-(1-hydroxy-2-{[6-(4-phenylbutoxy)hexyl]amino}ethyl)phenol
Salmeterol-fluticasone propionate mixt.
GIIZNNXWQWCKIB-UHFFFAOYSA-N
(+-)-4-Hydroxy-alpha1-(((6-(4-phenylbutoxy)hexyl)amino)methyl)-1,3-benzenedimethanol
(+-)-4-Hydroxy-alpha'-(((6-(4-phenylbutoxy)hexyl)amino)methyl
1,3-Benzenedimethanol, 4-hydroxy-α1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-, (±)- (ZCI)
4-Hydroxy-α1-[[[6-(4-phenylbutoxy)hexyl]amino]methyl]-1,3-benzenedimethanol (ACI)
2-(Hydroxymethyl)-4-[1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl]phenol
2-Hydroxymethyl-4-[1-hydroxy-2-[6-(4-phenyl-butoxy)-hexylamino]-ethyl]-phenol

MDL Number

MFCD00867037

Customs Code

2922509090

FAQ

What are the physical and chemical properties of Salmeterol (CAS: 89365-50-4)?

Salmeterol is a β2-adrenergic receptor agonist with a molecular formula of C23H28NO4. Its molecular weight is 364.49 g/mol. Salmeterol is sparingly soluble in water but soluble in ethanol. It has a crystalline form and is stable under normal storage conditions. It is not highly reactive under normal conditions but may degrade under heat or light exposure.

How is Salmeterol (CAS: 89365-50-4) typically synthesized?

Salmeterol is synthesized via a multi-step process involving the use of bromoacetic acid derivatives, aldehydes, and amino acids. Common synthesis methods include the use of palladium-catalyzed coupling reactions and asymmetric synthesis techniques. The yield and selectivity are typically high, with purification steps including recrystallization and chromatography.

What industries use Salmeterol (CAS: 89365-50-4)?

Salmeterol is primarily used in the pharmaceutical industry, specifically as an inhalation bronchodilator for the treatment of asthma and chronic obstructive pulmonary disease (COPD). It is also used in polymer manufacturing, where it can be incorporated into medical devices and other products requiring biocompatibility and stability.

What precautions should be taken when handling Salmeterol (CAS: 89365-50-4)?

When handling Salmeterol,佩戴个人防护装备 (PPE) 是必要的，包括手套、护目镜和实验室外套。应在通风橱中操作以避免吸入或皮肤接触。在储存时，应避免高温和直射阳光，存放在阴凉干燥处。发生泄漏时，应立即用大量水冲洗并寻求专业帮助。查阅安全数据表 (SDS) 以获取详细的安全信息。