Tetrahydro-3-furancarboxylic acid

Basic Information

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CAS Number

89364-31-8

Molecular Formula

C5H8O3

Molecular Weight

116.12 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Physical State

Pale-yellow to Yellow-brown Liquid

Boiling Point

140 °C/15 mmHg

Density

1.214 g/mL at 25 °C

Refractive Index

n20/D 1.4605(lit.)

SMILES

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C1COCC1C(=O)O

InChI

InChI=1S/C5H8O3/c6-5(7)4-1-2-8-3-4/h4H,1-3H2,(H,6,7)

InChIKey

BOTREHHXSQGWTR-UHFFFAOYSA-N

LogP

0.10750000000000015

Topological Polar Surface Area

46.53 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

99.8

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

CS-W004096
Tetrahydro-furan-3-carboxylic acid
FT-0772043
W-200520
(RS)-tetrahydro-furan-3-carboxylic acid
3-tetrahydrofuroic acid
SY016391
EN300-53423
BOTREHHXSQGWTR-UHFFFAOYSA-N
PB26265
(R)-Tetrahydro-3-furoic acid
Tetrahydro-3-furoic acid, contains 250 ppm BHT as inhibitor, 99%
3-tetrahydrofuran-carboxylic acid
tetrahydrofuran-3-carboxylicacid
racemic tetrahydro-furan-3-carboxylic acid
PB15879
rac-tetrahydro-3-furoic acid
3-Furancarboxylic acid, tetrahydro-
PS-3907
tetrahydrofuran-3-carboxylic acid
AM20120290
(+/-)-tetrahydro-3-furoic acid
J-502295
J-640086
SCHEMBL226904
(RS)-3-Tetrahydrofuroic acid
tetrahydro-furan-4-carboxylic acid
A26924
rac-tetrahydrofuran-3-carboxylic acid
3-Tetrahydrofuroic;tetrahydro-3-furancarboxylic acid;Tetrahydrofuran-3-carboxylic acid
J-502551

MDL Number

MFCD00075173

FAQ

What are the physical and chemical properties of Tetrahydro-3-furancarboxylic acid (CAS: 89364-31-8)?

Tetrahydro-3-furancarboxylic acid (CAS: 89364-31-8) is a white crystalline solid with a molecular weight of approximately 134.13 g/mol. It is slightly soluble in water and more soluble in organic solvents. This compound is known for its reactivity, particularly in esterification and condensation reactions.

How is Tetrahydro-3-furancarboxylic acid (CAS: 89364-31-8) typically synthesized?

Tetrahydro-3-furancarboxylic acid can be synthesized via the Strecker synthesis or by reduction of 3-cyclohexenone oxime. The Strecker method involves aminomethanation of aldehydes followed by hydrolysis, while the reduction method utilizes organometallic reagents or hydrogenation with a catalyst, achieving good selectivity and yield.

What industries use Tetrahydro-3-furancarboxylic acid (CAS: 89364-31-8)?

Tetrahydro-3-furancarboxylic acid (CAS: 89364-31-8) is used in various industries, including pharmaceuticals for the synthesis of certain drugs, polymers for the modification of materials, and sensors for detecting various analytes. Its applications are particularly relevant in the development of new chemical sensors and as a monomer in polymer synthesis.

What precautions should be taken when handling Tetrahydro-3-furancarboxylic acid (CAS: 89364-31-8)?

When handling Tetrahydro-3-furancarboxylic acid (CAS: 89364-31-8), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or fume hood to minimize inhalation risk. Store the compound under dry conditions and avoid contact with moisture. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage instructions.