N-Benzyl-5-bromo-2-chlorobenzamide

Basic Information

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CAS Number

892018-65-4

Molecular Formula

C14H11BrClNO

Molecular Weight

324.61 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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C1=CC=C(C=C1)CNC(=O)C2=C(C=CC(=C2)Br)Cl

InChI

InChI=1S/C14H11BrClNO/c15-11-6-7-13(16)12(8-11)14(18)17-9-10-4-2-1-3-5-10/h1-8H,9H2,(H,17,18)

InChIKey

KWPNVANLUVHVKN-UHFFFAOYSA-N

LogP

4.0325000000000015

Topological Polar Surface Area

29.1 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

281

Synonyms & References

English

AKOS001119654
892018-65-4
BENZYL 5-BROMO-2-CHLOROBENZAMIDE
N-Benzyl-5-bromo-2-chlorobenzamide
BS-23483
DTXSID10589614
MFCD04602185
Z27749663
Benzyl 5-bromo-2-chlorobenzamide

MDL Number

MFCD04602185

FAQ

What are the physical and chemical properties of N-Benzyl-5-bromo-2-chlorobenzamide (CAS: 892018-65-4)?

N-Benzyl-5-bromo-2-chlorobenzamide is a white crystalline solid with a molecular weight of approximately 322.03 g/mol. It has low solubility in water but is soluble in common organic solvents like ethanol and acetone. Chemically, it is stable but can react with strong bases to form the corresponding amine. This compound is often used in organic synthesis and pharmaceutical applications.

How is N-Benzyl-5-bromo-2-chlorobenzamide (CAS: 892018-65-4) typically synthesized?

N-Benzyl-5-bromo-2-chlorobenzamide is typically synthesized through the coupling of 2-chlorobenzamide with benzyl bromide in the presence of a base like potassium carbonate. The reaction yields the target compound with good selectivity and moderate to high yield depending on the reaction conditions.

What industries use N-Benzyl-5-bromo-2-chlorobenzamide (CAS: 892018-65-4)?

N-Benzyl-5-bromo-2-chlorobenzamide is primarily used in the pharmaceutical industry for the synthesis of various drugs and intermediates. It also finds applications in the polymer industry for creating novel materials and in the research of chemical sensors and semiconductors.

What precautions should be taken when handling N-Benzyl-5-bromo-2-chlorobenzamide (CAS: 892018-65-4)?

When handling N-Benzyl-5-bromo-2-chlorobenzamide, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using absorbent materials, and proper disposal methods should be followed. Always consult the Safety Data Sheet (SDS) for detailed safety information and procedures.