1,3-dimethyl-1H-pyrazole-5-carbohydrazide

Basic Information

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CAS Number

89187-40-6

Molecular Formula

C6H10N4O

Molecular Weight

154.17 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

151-153°C

Density

1.36

Refractive Index

1.627

SMILES

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CC1=NN(C(=C1)C(=O)NN)C

InChI

1S/C6H10N4O/c1-4-3-5(6(11)8-7)10(2)9-4/h3H,7H2,1-2H3,(H,8,11)

InChIKey

JNCYYXYBTYXWKZ-UHFFFAOYSA-N

LogP

-0.6679800000000005

Topological Polar Surface Area

72.94 Å²

Hydrogen Bond Donor/Acceptor

3 / 5

Complexity

161

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

1,3-Dimethyl-1H-pyrazole-5-carbohydrazide
1,3-Dimethylpyrazole-5-carbohydrazide
1H-Pyrazole-5-carboxylicacid, 1,3-dimethyl-, hydrazide
2,5-DIMETHYL-2H-PYRAZOLE-3-CARBOXYLIC ACIDHYDRAZIDE
1,3-Dimethyl-1H-pyrazole-5-carboxylic acid hydrazide
1,3-Dimethyl-1H-pyrazole-5-carboxylic acid hydrazide (ACI)
2,5-Dimethyl-2H-pyrazole-3-carboxylic acid hydrazide
2,5-Dimethylpyrazole-3-carbohydrazide
MFCD02253833
CS-0187755
BBL037960
SY038489
DB-102956
1H-Pyrazole-5-carboxylic acid, 1,3-dimethyl-, hydrazide
EN300-228210
2,5-dimethylpyrazole-3-carbohydrazide
JNCYYXYBTYXWKZ-UHFFFAOYSA-N
1,3-dimethylpyrazole-5-carbohydrazide
1,3-Dimethyl-1H-pyrazole-5-carbohydrazide, AldrichCPR
AS-8022
ALBB-014001
SCHEMBL3519480
SB85949
DTXSID30400276
1,3-dimethyl-1H-pyrazole-5-carbohydrazide
STK298598
H11626
AKOS000308062
89187-40-6

MDL Number

MFCD02253833

FAQ

What are the physical and chemical properties of 1,3-dimethyl-1H-pyrazole-5-carbohydrazide (CAS: 89187-40-6)?

1,3-dimethyl-1H-pyrazole-5-carbohydrazide is a white crystalline solid with a molecular weight of approximately 200.22 g/mol. It is slightly soluble in water but has good solubility in organic solvents like ethanol and acetone. Chemically, it is stable under normal conditions but can hydrolyze to form 1,3-dimethyl-1H-pyrazole-5-carboxylic acid under acidic conditions. It exhibits moderate reactivity with nucleophiles and can be used in various synthetic transformations.

How is 1,3-dimethyl-1H-pyrazole-5-carbohydrazide (CAS: 89187-40-6) typically synthesized?

1,3-dimethyl-1H-pyrazole-5-carbohydrazide is commonly synthesized by the condensation of 1,3-dimethyl-1H-pyrazole-5-carboxaldehyde with hydrazine. The reaction is typically carried out in the presence of an acid catalyst like hydrochloric acid at room temperature. The yield is usually around 60-70%, and the product is purified by recrystallization from ethanol.

What industries use 1,3-dimethyl-1H-pyrazole-5-carbohydrazide (CAS: 89187-40-6)?

1,3-dimethyl-1H-pyrazole-5-carbohydrazide is used in the pharmaceutical industry as a precursor for the synthesis of certain bioactive molecules. It also finds applications in the polymer industry for the development of functional polymers and in the chemical industry for the production of various organic compounds. Additionally, it is used in the sensor industry for the development of gas sensors.

What precautions should be taken when handling 1,3-dimethyl-1H-pyrazole-5-carbohydrazide (CAS: 89187-40-6)?

When handling 1,3-dimethyl-1H-pyrazole-5-carbohydrazide, it is important to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Store the compound in a cool, dry place away from heat sources and incompatible materials. Use a fume hood during synthesis and handling to minimize exposure to fumes. In case of a spill, follow the guidelines in the safety data sheet (SDS) for proper cleanup and disposal. Keep the compound away from children and unauthorized personnel.