Tert-butyl 4-(2-hydroxyethyl)piperidine-1-carboxylate

Basic Information

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CAS Number

89151-44-0

Molecular Formula

C12H23NO3

Molecular Weight

229.32 g/mol

Basic Physical Properties

Physical State

Colorless to Yellow Liquid

Boiling Point

120-150 °C/0.5 mmHg

Density

1.043 g/mL at 25 °C

Refractive Index

n20/D 1.4730(lit.)

SMILES

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CC(C)(C)OC(=O)N1CCC(CC1)CCO

InChI

InChI=1S/C12H23NO3/c1-12(2,3)16-11(15)13-7-4-10(5-8-13)6-9-14/h10,14H,4-9H2,1-3H3

InChIKey

YBNJZIDYXCGAPX-UHFFFAOYSA-N

LogP

2.0159000000000002

Topological Polar Surface Area

49.769999999999996 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

227

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

N-Boc-4-Piperidineethanol
N-(tert-Butoxycarbonyl)-4-piperidineethanol
4-(2-Hydroxyethyl)piperidine-1-carboxylic acid tert-butyl ester
1-BOC-4-(2-HYDROXYETHYL)PIPERIDINE
2-(3-(benzylaMino)oxetan-3-yl)ethanol
Boc-4-(2-hydroxyethyl) piperidine
N-BOC-4-piperidine-β-ethanol
N-tert-Butoxycarbonyl-4-piperidineethanol
tert-Butyl 4-(2-hydroxyethyl)piperidine-1-carboxylate
Boc-2-(4-piperidyl) ethanol
1-Boc-4-(2-hydroxy-ethyl)-piperidine
tert-butyl 4-(2-hydroxyethyl)piperidine-1-carboxylate
1,1-Dimethylethyl 4-(2-hydroxyethyl)-1-piperidinecarboxylate
1-Boc-4-(2-hydroxyethyl)piperidine
1-tert-Butoxycarbonyl-4-(2-hydroxyethyl)piperidine
1-tert-Butoxycarbonyl-4-piperidineethanol
2-(N-tert-Butoxycarbonyl-4-piperidinyl)ethanol
2-(N-tert-Butoxycarbonyl-4-piperidyl)ethanol
2-[1-(tert-Butoxycarbonyl)-4-piperidyl]ethanol
2-[1-(tert-Butoxycarbonyl)piperidin-4-yl]ethanol
4-(2-Hydroxy-ethyl)-piperidine-1-carboxylic acid tert-butyl ester
4-(2-Hydroxyethyl)-1-(tert-butoxycarbonyl)piperidine
4-(2-Hydroxyethyl)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester
N-(tert-Butoxycarbonyl)-4-(2-hydroxyethyl)piperidine
N-Boc-4-piperidineethanol
N-Boc-piperidineethanol
tert-Butyl 4-(2-hydroxyethyl)-1-piperidinecarboxylate
tert-Butyl 4-(2-hydroxyethyl)tetrahydropyridine-1(2H)-carboxylate
MFCD03427086
SCHEMBL310405
N-Boc-4-(2-hydroxyethyl)piperidine

MDL Number

MFCD03427086

Customs Code

2933399090

FAQ

What is Tert-butyl 4-(2-hydroxyethyl)piperidine-1-carboxylate (CAS: 89151-44-0)?

Tert-butyl 4-(2-hydroxyethyl)piperidine-1-carboxylate (CAS: 89151-44-0) is an organic compound with the chemical formula C10H21NO3. It belongs to the piperidine carboxylate family and features a tert-butyl group, a hydroxyethyl chain, and a carboxylate functional group. This compound is typically a white solid with solubility in polar solvents and is used as an intermediate in chemical synthesis.

What are the main uses of Tert-butyl 4-(2-hydroxyethyl)piperidine-1-carboxylate (CAS: 89151-44-0)?

Tert-butyl 4-(2-hydroxyethyl)piperidine-1-carboxylate (CAS: 89151-44-0) is primarily used in pharmaceutical research as a building block for drug development. It serves as an intermediate in the synthesis of active pharmaceutical ingredients (APIs) and may find applications in polymer science, organic chemistry, and as a chelating agent. Its unique structure makes it valuable in creating compounds with specific biological activities.

Is Tert-butyl 4-(2-hydroxyethyl)piperidine-1-carboxylate (CAS: 89151-44-0) safe?

Tert-butyl 4-(2-hydroxyethyl)piperidine-1-carboxylate (CAS: 89151-44-0) is generally considered safe when handled properly, but it may cause mild skin or eye irritation. Safety data sheets (SDS) recommend using appropriate personal protective equipment (PPE) like gloves and goggles. It is not classified as highly toxic, but standard laboratory safety protocols should be followed to ensure safe handling and exposure limits.

How should Tert-butyl 4-(2-hydroxyethyl)piperidine-1-carboxylate (CAS: 89151-44-0) be stored?

Tert-butyl 4-(2-hydroxyethyl)piperidine-1-carboxylate (CAS: 89151-44-0) should be stored in a sealed container at room temperature (15-25°C), away from moisture and direct light. It maintains stability under normal conditions but requires protection from humidity and heat to prevent degradation. Proper storage ensures its chemical integrity and prolongs shelf life.