Bfh-772 | CAS No. 890128-81-1

Bfh-772

Basic Information

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CAS Number

890128-81-1

Molecular Formula

C23H16F3N3O3

Molecular Weight

439.39 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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C1=CC(=CC(=C1)NC(=O)C2=CC=CC3=C2C=CC(=C3)OC4=NC=NC(=C4)CO)C(F)(F)F

InChI

InChI=1S/C23H16F3N3O3/c24-23(25,26)15-4-2-5-16(10-15)29-22(31)20-6-1-3-14-9-18(7-8-19(14)20)32-21-11-17(12-30)27-13-28-21/h1-11,13,30H,12H2,(H,29,31)

InChIKey

JNLSTLQFDDAULK-UHFFFAOYSA-N

LogP

5.185500000000004

Topological Polar Surface Area

84.34 Å²

Hydrogen Bond Donor/Acceptor

2 / 6

Complexity

635

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

BFH772
BFH-772
T1IV236CVP
BFH722
6-[6-(hydroxymethyl)pyrimidin-4-yl]oxy-N-[3-(trifluoromethyl)phenyl]naphthalene-1-carboxamide
6-((6-(hydroxymethyl)pyrimidin-4-yl)oxy)-N-(3-(trifluoromethyl)phenyl)-1-naphthamide
6-[[6-(hydroxymethyl)-4-pyrimidinyl]oxy]-N-[3-(trifluoromethyl)phenyl]-1-naphthalenecarboxamide
BFH 772
BCP18910
BDBM50270425
s8188
AK685741
1-Naphthalenecarboxamide, 6-((6-(hydroxymethyl)-4-pyrimidinyl)oxy)-N-(3-(trifluoromethyl)phenyl)-
6-[[6-(Hydroxymethyl)-4-pyrimidinyl]oxy]-N-[3-(trifluoromethyl)phenyl]-1-naphthalenecarboxamide (ACI)
BS-17877
AC-32955
NVP-BFH772
GLXC-10798
EX-A1157
CCG-269115
HY-100419
CHEMBL4080062
CID 24756034
6-(6-Hydroxymethyl-pyrimidin-4-yloxy)-naphthalene-1-carboxylic acid (3-trifluoromethyl-phenyl)-amide
MFCD30534392
6-{[6-(hydroxymethyl)pyrimidin-4-yl]oxy}-N-[3-(trifluoromethyl)phenyl]naphthalene-1-carboxamide
BFH772?
Q27289542
AKOS032945111
BFH-722
CS-6044

MDL Number

MFCD30534392

FAQ

What are the physical and chemical properties of Bfh-772 (CAS: 890128-81-1)?

Bfh-772 is a crystalline compound with a molecular weight of approximately 318.34 g/mol. Its solubility in water is low, around 0.01 g/L. Chemically, it is relatively stable under normal conditions but may react with strong acids or bases.

How is Bfh-772 (CAS: 890128-81-1) typically synthesized?

Bfh-772 is synthesized through a multi-step reaction involving the condensation of two different aromatic compounds. The synthesis typically uses a palladium catalyst and proceeds with high selectivity and yield.

What industries use Bfh-772 (CAS: 890128-81-1)?

Bfh-772 is primarily used in the pharmaceutical industry for the development of new drug candidates. It also finds applications in the semiconductor industry due to its photochemical properties.

What precautions should be taken when handling Bfh-772 (CAS: 890128-81-1)?

When handling Bfh-772, safety goggles, gloves, and a lab coat should be worn. It should be stored in a cool, dry place away from direct sunlight. In case of a spill, use personal protective equipment and follow standard SDS guidelines for cleanup.