Methyl 4-amino-6-methylnicotinate

Basic Information

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CAS Number

886372-01-6

Molecular Formula

C8H10N2O2

Molecular Weight

166.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Boiling Point

292.1±35.0 °C at 760 mmHg

Density

1.2±0.1 g/cm3

Flash Point

130.4±25.9 °C

Vapor Pressure

0.0±0.6 mmHg at 25°C

SMILES

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CC1=CC(=C(C=N1)C(=O)OC)N

InChI

InChI=1S/C8H10N2O2/c1-5-3-7(9)6(4-10-5)8(11)12-2/h3-4H,1-2H3,(H2,9,10)

InChIKey

PVOKIMNZYVHOJH-UHFFFAOYSA-N

LogP

0.7588199999999998

Topological Polar Surface Area

65.21 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

172

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

4-氨基-6-甲基烟酸甲酯
Methyl 4-amino-6-methylnicotinate
methyl 4-amino-6-methylpyridine-3-carboxylate
SB21615
AK321488
Methyl 4-amino-6-methyl-3-pyridinecarboxylate (ACI)
CS-0049057
MFCD07374917
AKOS006286322
SCHEMBL10330645
DS-11915
Methyl4-amino-6-methylnicotinate
4-AMINO-6-METHYL-NICOTINIC ACID METHYL ESTER
P18775
886372-01-6

MDL Number

MFCD07374917

FAQ

What are the physical and chemical properties of Methyl 4-amino-6-methylnicotinate (CAS: 886372-01-6)?

Methyl 4-amino-6-methylnicotinate is a crystalline compound with a molecular weight of approximately 193.23 g/mol. It has a solubility of about 0.1 g/100 mL in water. This compound is moderately reactive and may undergo hydrolysis under acidic or basic conditions. It is also susceptible to thermal decomposition at high temperatures.

How is Methyl 4-amino-6-methylnicotinate (CAS: 886372-01-6) typically synthesized?

Methyl 4-amino-6-methylnicotinate is typically synthesized via condensation of 6-methylpyridine-3-carboxylic acid with methylamine followed by methylation. This process requires the use of appropriate catalysts and solvents. The yield can be improved by optimizing reaction conditions such as temperature and time.

What industries use Methyl 4-amino-6-methylnicotinate (CAS: 886372-01-6)?

Methyl 4-amino-6-methylnicotinate is used in the pharmaceutical industry for synthesizing various drugs. It also finds applications in the development of sensors and in the production of certain polymers. Its reactivity and specific functional groups make it valuable in these fields.

What precautions should be taken when handling Methyl 4-amino-6-methylnicotinate (CAS: 886372-01-6)?

When handling Methyl 4-amino-6-methylnicotinate, it is important to use personal protective equipment (PPE) such as gloves and safety goggles. Store it in a cool, dry place away from heat and moisture. In case of a spill, contain it with appropriate absorbents and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed information.