LY2119620 | CAS No. 886047-22-9

LY2119620

Basic Information

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CAS Number

886047-22-9

Molecular Formula

C19H24ClN5O3S

Molecular Weight

437.95 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Density

1.46±0.1 g/cm3 (20 ºC 760 Torr),

SMILES

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CC1=C2C(=C(SC2=NC(=C1Cl)OCC(=O)N3CCN(CC3)C)C(=O)NC4CC4)N

InChI

InChI=1S/C19H24ClN5O3S/c1-10-13-15(21)16(17(27)22-11-3-4-11)29-19(13)23-18(14(10)20)28-9-12(26)25-7-5-24(2)6-8-25/h11H,3-9,21H2,1-2H3,(H,22,27)

InChIKey

TYTGOXSAAQWLPJ-UHFFFAOYSA-N

LogP

1.8853199999999992

Topological Polar Surface Area

100.78999999999999 Å²

Hydrogen Bond Donor/Acceptor

3 / 8

Complexity

631

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

3-Amino-5-chloro-n-cyclopropyl-4-methyl-6-(2-(4-methylpiperazin-1-yl)-2-oxoethoxy)thieno[2,3-b]pyridine-2-carboxamide
LY 2119620
Thieno[2,3-b]pyridine-2-carboxamide, 3-amino-5-chloro-N-cyclopropyl-4-methyl-6-[2-(4-methyl-1-piperazinyl)-2-oxoethoxy]-
LY2119620
3-Amino-5-chloro-N-cyclopropyl-4-methyl-6-[2-(4-methyl-1-piperazinyl)-2-oxoethoxy]thieno[2,3-b]pyridine-2-carboxamide (ACI)
HMS3886J13
LY-2119620
CCG-269103
BCP11632
3-amino-5-chloro-N-cyclopropyl-4-methyl-6-(2-(4-methylpiperazin-1-yl)-2-oxoethoxy)thieno(2,3-b)pyridine-2-carboxamide
CHEMBL4089376
AKOS027288959
3-Amino-5-Chloro-N-Cyclopropyl-4-Methyl-6-[2-(4-Methylpiperazin-1-Yl)-2-Oxoethoxy]thieno[2,3-B]pyridine-2-Carboxamide
DB-228544
Q27082623
NCGC00386411-02
GTPL6938
EX-A1875
BS-18215
3-Amino-5-chloro-N-cyclopropyl-4-methyl-6-[2-(4-methyl-1-piperazinyl)-2-oxoethoxy]thieno[2,3-b]pyridine-2-carboxamide; LY 2119620
SB19524
BDBM50265999
LY2119620?
SCHEMBL12049534
D70859
HY-15885
LY2119620 positive allosteric modulator of M2/M4 receptor
2CU
886047-22-9
AC-35548
s7366

MDL Number

MFCD27996043

FAQ

What is LY2119620 (CAS: 886047-22-9)?

LY2119620 (CAS: 886047-22-9) is a chemical compound used primarily in biomedical research and drug development. It is a potent inhibitor of the insulin-like growth factor-1 receptor (IGF-1R), which makes it useful for studying cellular proliferation and cancer biology.

What are the main uses of LY2119620 (CAS: 886047-22-9)?

LY2119620 (CAS: 886047-22-9) is mainly used in academic and pharmaceutical research as a selective IGF-1R inhibitor. It is also studied for its potential in cancer therapy and as a tool for cell biology research, particularly in understanding signaling pathways and drug resistance.

Is LY2119620 (CAS: 886047-22-9) safe?

LY2119620 (CAS: 886047-22-9) is generally considered safe for laboratory use under appropriate handling conditions. However, it is important to follow all safety guidelines, wear appropriate personal protective equipment, and store it in a secure, labeled container away from direct sunlight and heat sources.

How should LY2119620 (CAS: 886047-22-9) be stored?

LY2119620 (CAS: 886047-22-9) should be stored in a cool, dry place away from direct sunlight and heat sources. It should be kept in a tightly sealed container and protected from moisture. Store it at room temperature (15-30°C) to maintain its stability and potency. Avoid exposure to high temperatures and flammable materials.