1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclobutanecarboxylic acid | CAS No. 885951-77-9

1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclobutanecarboxylic acid

Basic Information

CAS Number

885951-77-9

Molecular Formula

C20H19NO4

Molecular Weight

337.38 g/mol

AD

Basic Physical Properties

Boiling Point

574.7℃ at 760 mmHg

C1CC(C1)(C(=O)O)NC(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

InChI

InChI=1S/C20H19NO4/c22-18(23)20(10-5-11-20)21-19(24)25-12-17-15-8-3-1-6-13(15)14-7-2-4-9-16(14)17/h1-4,6-9,17H,5,10-12H2,(H,21,24)(H,22,23)

InChIKey

QGLSMDZVGLRTKH-UHFFFAOYSA-N

LogP

3.5324000000000026

Topological Polar Surface Area

75.63000000000001 Ų

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

508

Safety Information

View Safety Information

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

  • Fmoc-1-Amino-1-cyclobutanecarboxylic acid
  • Cyclobutanecarboxylicacid, 1-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-
  • Fmoc-1-aminocyclobutane-1-carboxylic acid
  • Fmoc-1-Aminocyclobutanecarboxylic acid
  • Fmoc-AC4C-OH
  • 1-(Fmoc-amino)cyclobutanecarboxylic acid
  • Fmoc-cyclovaline
  • Fmoc-1-aminio-1-cyclobutane carboxylic acid
  • 1-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]cyclobutanecarboxylic acid (ACI)
  • 1-([[(9H-Fluoren-9-yl)methoxy]carbonyl]amino)cyclobutane-1-carboxylic acid
  • 1-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]cyclobutane-1-carboxylic acid
  • 1-({[(9H-FLUOREN-9-YL)METHOXY]CARBONYL}AMINO)CYCLOBUTANE-1-CARBOXYLIC ACID
  • 1-(((9H-fluoren-9-yl)methoxy)carbonylamino)cyclobutanecarboxylic acid
  • QGLSMDZVGLRTKH-UHFFFAOYSA-N
  • EN300-623994
  • 1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclobutanecarboxylic acid
  • Fmoc-1-amino-1-cyclobutane carboxylic acid
  • Fmoc-1-amino-1-cyclobutanecarboxylic acid
  • 1-(9H-fluoren-9-ylmethoxycarbonylamino)cyclobutane-1-carboxylic Acid
  • Z1200999164
  • DTXSID60363749
  • 1-(Fmoc-amino)cyclobutanecarboxylic acid, >=95.0% (HPLC)
  • SY059480
  • 1-(9H-Fluoren-9-ylmethoxy carbonylamino)-cyclobutanecarboxylic acid
  • CS-0130262
  • MFCD02682624
  • SCHEMBL178778
  • Fmoc-Acb(1)-OH
  • 1-(9-Fluorenylmethyloxycarbonylamino)-cyclobutyl-1-carboxylic acid
  • AKOS015889711
  • GS-5509

MDL Number

MFCD02682624

FAQ

What are the physical and chemical properties of 1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclobutanecarboxylic acid (CAS: 885951-77-9)?

1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclobutanecarboxylic acid (CAS: 885951-77-9) is a solid at room temperature with a high molecular weight of approximately 491. It is slightly soluble in water. It is highly reactive, especially towards nucleophiles, and exhibits good stability in most organic solvents. This compound is often used in the synthesis of bioactive molecules and as a building block in organic chemistry.

How is 1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclobutanecarboxylic acid (CAS: 885951-77-9) typically synthesized?

1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclobutanecarboxylic acid (CAS: 885951-77-9) is synthesized through a multi-step process involving the activation of a fluorene derivative, followed by its coupling with cyclobutanecarboxylic acid. The synthesis typically employs coupling reagents like HATU or EDC in the presence of a base, with yields around 70%.

What industries use 1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclobutanecarboxylic acid (CAS: 885951-77-9)?

This compound is used in the pharmaceutical and materials industry. In pharmaceuticals, it serves as a key intermediate in the synthesis of bioactive molecules and drugs. In the materials industry, it is utilized in the development of new polymers and sensors due to its reactive nature and unique structural features.

What precautions should be taken when handling 1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclobutanecarboxylic acid (CAS: 885951-77-9)?

When handling 1-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)cyclobutanecarboxylic acid (CAS: 885951-77-9), it is important to wear appropriate Personal Protective Equipment (PPE), including gloves, goggles, and a lab coat. Ensure that the work is done in a well-ventilated area or a fume hood. Spills should be cleaned up immediately using an appropriate solvent. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.

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