2,6-Dichloropyridine-4-methylamine

Basic Information

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CAS Number

88579-63-9

Molecular Formula

C6H6Cl2N2

Molecular Weight

177.03 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

291.912°C at 760 mmHg

Density

1.399

Flash Point

130.344°C

Refractive Index

1.588

SMILES

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C1=C(C=C(N=C1Cl)Cl)CN

InChI

InChI=1S/C6H6Cl2N2/c7-5-1-4(3-9)2-6(8)10-5/h1-2H,3,9H2

InChIKey

LCVQJXXKYFOSGH-UHFFFAOYSA-N

LogP

1.8471

Topological Polar Surface Area

38.91 Å²

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

99.9

Synonyms & References

English

2,6-Dichloropyridine-4-methylamine
4-Aminomethyl-2,6-dichloropyridine
(2,6-dichloropyridin-4-yl)methanamine
2,6-dichloro- 4-Pyridinemethanamine
(2,6-dichloro-4-pyridyl)methylamine
(2,6-dichloropyridin-4-yl)methylamine
4-(Aminomethyl)-2,6-dichloropyridine
4-Pyridinemethanamine,2,6-dichloro
C-(2,6-Dichlor-[4]pyridyl)-methylamin
C-(2,6-dichloro-[4]pyridyl)-methylamine
4-Pyridinemethanamine,2,6-dichloro-
4-Pyridinemethanamine, 2,6-dichloro-
PubChem19577
LCVQJXXKYFOSGH-UHFFFAOYSA-N
SBB052432
OR9190
FCH921288
KM2668
CD
(2,6-dichloro-4-pyridyl)methanamine
2,6-Dichloro-4-pyridinemethanamine (ACI)
(2,6-Dichloropyridin-4-yl)methanamine
2,6-Dichloropyridine-4-methanamine
DTXSID20465379
2,6-DICHLORO-4-PYRIDINEMETHANAMINE
CS-0091258
88579-63-9
AKOS006343482
AB23327
DB-078005
F11144

MDL Number

MFCD06212867

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2,6-Dichloropyridine-4-methylamine (CAS: 88579-63-9)?

2,6-Dichloropyridine-4-methylamine (CAS: 88579-63-9) is a white or light yellow crystalline solid with a molecular weight of approximately 228.05 g/mol. It is slightly soluble in water but soluble in common organic solvents like ethanol and acetone. The compound is moderately reactive, particularly towards nucleophiles and reducing agents. It is a Lewis base and can form coordination complexes with transition metals.

How is 2,6-Dichloropyridine-4-methylamine (CAS: 88579-63-9) typically synthesized?

2,6-Dichloropyridine-4-methylamine (CAS: 88579-63-9) is typically synthesized by a multi-step process involving the reaction of 2,6-dichloropyridine with methylamine under basic conditions. The reaction involves the substitution of a chloro group by the amino group, followed by an aminomethylation. Common solvents include dimethylformamide (DMF), and the reaction is often catalyzed by a base like potassium carbonate. The overall yield is around 70-80%.

What industries use 2,6-Dichloropyridine-4-methylamine (CAS: 88579-63-9)?

2,6-Dichloropyridine-4-methylamine (CAS: 88579-63-9) is used in various industries, including pharmaceuticals, where it serves as a precursor in the synthesis of bioactive compounds. It is also utilized in the production of organic light-emitting diodes (OLEDs) due to its electronic properties. Additionally, it finds applications in the development of sensors and as a reagent in polymer chemistry.

What precautions should be taken when handling 2,6-Dichloropyridine-4-methylamine (CAS: 88579-63-9)?

When handling 2,6-Dichloropyridine-4-methylamine (CAS: 88579-63-9), it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be used in a well-ventilated area or a fume hood to minimize inhalation risks. Spills should be cleaned up using appropriate absorbent materials and wiped down with water. Always consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.