Hexapeptide-9 | CAS No. 885024-94-2

Hexapeptide-9

Basic Information

CAS Number

885024-94-2

Molecular Formula

C24H38N8O9

Molecular Weight

582.61 g/mol

AD

Basic Physical Properties

Boiling Point

1205.4±65.0 °C(Predicted)

Density

1.413±0.06 g/cm3(Predicted)

C1CC(N(C1)C(=O)CN)C(=O)NC(CCC(=O)N)C(=O)NCC(=O)N2CCCC2C(=O)NC(CCC(=O)N)C(=O)O

InChI

InChI=1S/C24H38N8O9/c25-11-19(35)31-9-1-3-15(31)22(38)29-13(5-7-17(26)33)21(37)28-12-20(36)32-10-2-4-16(32)23(39)30-14(24(40)41)6-8-18(27)34/h13-16H,1-12,25H2,(H2,26,33)(H2,27,34)(H,28,37)(H,29,38)(H,30,39)(H,40,41)/t13-,14-,15-,16-/m0/s1

InChIKey

OGNHOGPWQTWKGQ-VGWMRTNUSA-N

LogP

-4.371500000000002

pKa

3.53±0.10(Predicted)

Topological Polar Surface Area

277.42 Ų

Hydrogen Bond Donor/Acceptor

10 / 17

Complexity

1050

Synonyms & References

English

  • L-Glutamine, glycyl-L-prolyl-L-glutaminylglycyl-L-prolyl-
  • L-GLUTAMINE, GLYCYL-L-PROLYL-L-GLUTAMINYLGLYCYL-L-PROLYL-
  • Glycyl-L-prolyl-L-glutaminylglycyl-L-prolyl-L-glutamine (ACI)
  • 2: PN: IE20060154 PAGE: 25 claimed protein
  • 4: PN: KR20190064307 SEQID: 4 claimed sequence
  • Collaxyl
  • Hexapeptide 9
  • Hexapeptide-9
  • Glycyl-L-prolyl-L-glutaminylglycyl-L-prolyl-L-glutamine
  • Apepbiosix-5
  • Gly-Pro-Gln-Gly-Pro-Gln
  • L25414IE41
  • (2S)-5-Amino-2-[[(2S)-1-[2-[[(2S)-5-amino-2-[[(2S)-1-(2-aminoacetyl)pyrrolidine-2-carbonyl]amino]-5-oxopentanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-5-oxopentanoic acid
  • Hexapeptide-9 [INCI]
  • Hexapeptide-9 (acetate)
  • SCHEMBL4726314
  • Hexapeptide-9?
  • 885024-94-2
  • CS-0166872
  • G66155
  • HY-P3163
  • UNII-L25414IE41
  • DA-64128

FAQ

What are the physical and chemical properties of Hexapeptide-9 (CAS: 885024-94-2)?

Hexapeptide-9 (CAS: 885024-94-2) is a crystalline compound with a molecular weight of approximately 852.6 g/mol. It has a high solubility in water and is stable under neutral pH conditions. Hexapeptide-9 exhibits weak reactivity with common reagents and is generally stable under standard laboratory conditions.

How is Hexapeptide-9 (CAS: 885024-94-2) typically synthesized?

Hexapeptide-9 (CAS: 885024-94-2) is commonly synthesized through solid-phase peptide synthesis (SPPS) using Fmoc chemistry. The synthesis typically involves the stepwise addition of amino acids, with deprotection and coupling reactions at each step. The yield is usually around 70-80%, and the final product is purified by reverse-phase HPLC.

What industries use Hexapeptide-9 (CAS: 885024-94-2)?

Hexapeptide-9 (CAS: 885024-94-2) is primarily used in the pharmaceutical industry for its potential anti-aging and skin care properties. It is also explored in the cosmetics industry for enhancing skin hydration and elasticity. Additionally, it has some applications in the food industry for improving the sensory characteristics of food products.

What precautions should be taken when handling Hexapeptide-9 (CAS: 885024-94-2)?

When handling Hexapeptide-9 (CAS: 885024-94-2), it is important to wear appropriate personal protective equipment (PPE), including gloves and safety goggles. It should be stored in a cool, dry place away from direct sunlight and heat sources. In the event of a spill, it should be contained and cleaned up using appropriate procedures in a fume hood. Refer to the Safety Data Sheet (SDS) for detailed handling and disposal instructions.

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