(s)-1-Boc-piperidine-3-carboxylic acid

Basic Information

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CAS Number

88495-54-9

Molecular Formula

C11H19NO4

Molecular Weight

229.28 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

165-169 °C

Boiling Point

165-169°C

Density

1.164

Flash Point

167.4℃

Refractive Index

1.496

Vapor Pressure

No data available

Specific Rotation

+53 ~ +61° (c=1, chloroform)

SMILES

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CC(C)(C)OC(=O)N1CCCC(C1)C(=O)O

InChI

InChI=1S/C11H19NO4/c1-11(2,3)16-10(15)12-6-4-5-8(7-12)9(13)14/h8H,4-7H2,1-3H3,(H,13,14)/t8-/m0/s1

InChIKey

NXILIHONWRXHFA-QMMMGPOBSA-N

LogP

1.7181

Topological Polar Surface Area

66.84 Å²

Hydrogen Bond Donor/Acceptor

1 / 5

Complexity

282

Safety Information

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GHS Hazard Pictograms

H319

H400

Hazard Statement

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H400 Very toxic to aquatic life
Hazardous to the aquatic environment, acute hazard

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

(S)-N-Boc-Piperidine-3-carboxylic acid
(S)-Boc-Nip-OH
1,3-Piperidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (3S)-
3-S-(+)-BOC-piperidinecarboxylic acid
S-1-Boc-piperidine-3-carboxylic acid
(S )-1-Boc-piperidine-3-carboxylic acid
(S)-1-(tert-butoxycarbonyl)piperidine-3-carboxylic acid
(S)-N-Boc-nipecotic acid
Boc-(S)-nipecotic acid
Boc-L-nipecotic acid
L-1-Boc-Nipecotic acid
N-Boc-(S)-Nipecotic acid
S-Boc-Nipecotic acid
1-tert-Butoxycarbonylpiperidine-3-carboxylic acid
Boc-
(S)-N-Boc-piperidine-3-carboxylic acid
(3S)-1-tert-butoxycarbonylpiperidine-3-carboxylic acid
1,3-Piperidinedicarboxylic acid, 1-(1,1-dimethylethyl) ester, (S)- (ZCI)
1-(1,1-Dimethylethyl) (3S)-1,3-piperidinedicarboxylate (ACI)
(3S)-1-(tert-Butoxycarbonyl)-3-piperidinecarboxylic acid
(3S)-1-(tert-Butoxycarbonyl)piperidine-3-carboxylic acid
(3S)-1-[(2-Methylpropan-2-yl)oxycarbonyl]piperidine-3-carboxylic acid
(3S)-1-[[(1,1-Dimethylethyl)oxy]carbonyl]-3-piperidinecarboxylic acid
(S)-(+)-N-Boc-nipecotic acid
(S)-1-(tert-Butoxycarbonyl)piperidine-3-carboxylic acid
(S)-1-Boc-piperidine-3-carboxylic Acid
(S)-Boc-nipecotic acid
(S)-N-(tert-Butoxycarbonyl)nipecotic acid
(S)-N-(tert-Butoxycarbonyl)piperidine-3-carboxylic acid
tert-Butyl (S)-3-carboxypiperidine-1-carboxylate
(s)-piperidine-1,3-dicarboxylic acid 1-tert-butyl ester

MDL Number

MFCD02179172

Customs Code

2933399090

FAQ

What is (s)-1-Boc-piperidine-3-carboxylic acid (CAS: 88495-54-9)?

(s)-1-Boc-piperidine-3-carboxylic acid is an organic compound with the chemical formula C9H17NO4. It is a chiral amide derivative with a (s)-configuration. This compound is used as an intermediate in organic synthesis and pharmaceuticals due to its structural characteristics.

What are the main uses of (s)-1-Boc-piperidine-3-carboxylic acid (CAS: 88495-54-9)?

(s)-1-Boc-piperidine-3-carboxylic acid is primarily used as a protecting group in organic synthesis and as a building block in the pharmaceutical industry for the synthesis of various drugs and natural products. It is also utilized in academic research for studying organic reactions and molecular interactions.

Is (s)-1-Boc-piperidine-3-carboxylic acid (CAS: 88495-54-9) safe?

(s)-1-Boc-piperidine-3-carboxylic acid is generally considered safe for laboratory use when handled with appropriate precautions. It is non-toxic, but contact with the eyes should be avoided. Proper ventilation is recommended during handling. Storage in a cool, dry place is advised, away from direct sunlight and heat sources.

How should (s)-1-Boc-piperidine-3-carboxylic acid (CAS: 88495-54-9) be stored?

(s)-1-Boc-piperidine-3-carboxylic acid should be stored in a cool, dry place, away from direct sunlight and heat sources. It should be kept in a tightly sealed container to protect it from moisture. Optimal storage conditions include a temperature range of 15-25°C and a relative humidity below 50%. Avoid contact with oxidizing agents and store in a chemical fume hood for safety purposes.