2-Fluoro-4-iodonicotinic acid

Basic Information

View in Editor

CAS Number

884494-51-3

Molecular Formula

C6H3FINO2

Molecular Weight

267 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Boiling Point

347°C at 760 mmHg

Density

2.198

Flash Point

163.7°C

Refractive Index

1.647

SMILES

View in Editor

C1=CN=C(C(=C1I)C(=O)O)F

InChI

InChI=1S/C6H3FINO2/c7-5-4(6(10)11)3(8)1-2-9-5/h1-2H,(H,10,11)

InChIKey

QKPLTGKHTYHYLU-UHFFFAOYSA-N

LogP

1.5235

Topological Polar Surface Area

50.19 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

167

Synonyms & References

English

2-Fluoro-4-iodonicotinic acid
2-Fluoro-4-iodo-nicotinic acid
2-Fluoro-4-iodopyridin-3-ylcaboxylic acid
2-fluoro-4-iodopyridine-3-carboxylic acid
3-Pyridinecarboxylicacid, 2-fluoro-4-iodo-
2-Fluoro-4-IodonicotinicAcid
PubChem17043
KSC446C8B
QKPLTGKHTYHYLU-UHFFFAOYSA-N
BCP27284
FCH1328268
PC49358
2-fluoro-4-iodonicotinic acid, AldrichCPR
AX8037098
ST2409987
2-Fluoro-4-iodo-3-pyridinecarboxylic acid (ACI)
AKOS015853203
J-509406
2-fluoro-4-iodonicotinic acid
DTXSID70660498
2-Fluoro-4-iodonicotinic acid, 95%
CS-0041297
DS-0726
884494-51-3
AC-33417
SCHEMBL198077
2-Fluoro-4-iodo-pyridine-3-carboxylic acid
2-fluoro-4-iodo-nicotinic acid
2-Fluoro-4-IodonicotinicAcidMethylEster
SY022347
MFCD03095310

MDL Number

MFCD03095310

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2-Fluoro-4-iodonicotinic acid (CAS: 884494-51-3)?

2-Fluoro-4-iodonicotinic acid is a crystalline solid with a molecular weight of approximately 289.01 g/mol. It has a low solubility in water but is more soluble in organic solvents like acetone and dimethylformamide. This compound is known for its limited reactivity under normal conditions, making it stable in most chemical environments.

How is 2-Fluoro-4-iodonicotinic acid (CAS: 884494-51-3) typically synthesized?

2-Fluoro-4-iodonicotinic acid can be synthesized through a iodination reaction of 2-fluoronicotinic acid with iodine in the presence of a base such as sodium hydroxide. The reaction conditions should be carefully controlled to achieve high selectivity and yield.

What industries use 2-Fluoro-4-iodonicotinic acid (CAS: 884494-51-3)?

2-Fluoro-4-iodonicotinic acid is primarily used in the pharmaceutical industry for the development of certain drugs due to its unique chemical structure. It may also be used in research and development for its potential applications in sensor technology and material science.

What precautions should be taken when handling 2-Fluoro-4-iodonicotinic acid (CAS: 884494-51-3)?

When handling 2-Fluoro-4-iodonicotinic acid, appropriate personal protective equipment such as gloves, goggles, and a lab coat should be worn. The compound should be handled in a well-ventilated area or a fume hood. In case of spillage, it is recommended to clean up using appropriate safety measures and consult the Safety Data Sheet (SDS) for detailed instructions.