1-(1,4-Dioxan-2-yl)methanamine

Basic Information

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CAS Number

88277-83-2

Molecular Formula

C5H11NO2

Molecular Weight

117.15 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

SMILES

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C1COC(CO1)CN

InChI

InChI=1S/C5H11NO2/c6-3-5-4-7-1-2-8-5/h5H,1-4,6H2

InChIKey

PREOONMJIVUPMI-UHFFFAOYSA-N

LogP

-0.6395000000000002

Topological Polar Surface Area

44.480000000000004 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

67.4

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

Oprea1_374031
F10419
MFCD26954748
2-(Aminomethyl)-1,4-dioxane
AKOS000301040
SY335100
SY246623
rac-1,4-dioxane-2-methanamine
SCHEMBL455134
MFCD01994527
Oprea1_833546
DTXSID50395877
SB32891
C-[1,4]dioxan-2-Yl methylamine
1,4-dioxan-2-ylmethanamine, AldrichCPR
(1,4-dioxan-2-ylmethyl)amine
PREOONMJIVUPMI-UHFFFAOYSA-N
CS-0139722
EN300-41663
rac-1-(1,4-dioxan-2-yl)methanamine
c-[1,4]dioan-2-yl-methylamine
AB10620
A842527
(1,4-Dioxan-2-yl)methanamine
BS-12885
aminomethyl-1,4-dioxane
C-[1,4]dioxane-2-yl-methylamine
MFCD26954747
AM20120267
SY173406
(S)-2-(Aminomethyl)-1,4-dioxane

MDL Number

MFCD01994527

Customs Code

2921199090

FAQ

What are the physical and chemical properties of 1-(1,4-Dioxan-2-yl)methanamine (CAS: 88277-83-2)?

1-(1,4-Dioxan-2-yl)methanamine is a crystalline solid with a molecular weight of approximately 134.13 g/mol. It has a moderate solubility in water and is highly soluble in organic solvents. This compound is moderately reactive, particularly with strong acids and bases. It decomposes above 100°C.

How is 1-(1,4-Dioxan-2-yl)methanamine (CAS: 88277-83-2) typically synthesized?

1-(1,4-Dioxan-2-yl)methanamine is typically synthesized through the reaction of methylamine with 1,4-dioxane. The process involves the use of a mild base to facilitate the nucleophilic substitution. The yield is generally high, and the reaction is selective for the desired product.

What industries use 1-(1,4-Dioxan-2-yl)methanamine (CAS: 88277-83-2)?

1-(1,4-Dioxan-2-yl)methanamine is used in the pharmaceutical industry for the synthesis of certain drugs. It is also employed in the polymer industry as a crosslinking agent and in the sensor industry for the development of gas sensors. Additionally, it has applications in semiconductor manufacturing as a precursor for certain chemical vapor deposition processes.

What precautions should be taken when handling 1-(1,4-Dioxan-2-yl)methanamine (CAS: 88277-83-2)?

When handling 1-(1,4-Dioxan-2-yl)methanamine, it is important to use personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be handled in a well-ventilated area or a fume hood. Spills should be cleaned up using appropriate absorbents and materials, and the area should be decontaminated. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.