5-Bromo-6-(trifluoromethyl)pyridin-2-amine | CAS No. 882500-21-2

5-Bromo-6-(trifluoromethyl)pyridin-2-amine

Basic Information

CAS Number

882500-21-2

Molecular Formula

C6H4BrF3N2

Molecular Weight

241.01 g/mol

AD

Basic Physical Properties

Boiling Point

218.1℃ at 760 mmHg

Density

1.790

Flash Point

85.7℃

C1=CC(=NC(=C1Br)C(F)(F)F)N

InChI

InChI=1S/C6H4BrF3N2/c7-3-1-2-4(11)12-5(3)6(8,9)10/h1-2H,(H2,11,12)

InChIKey

DNDAEASRGBLZCN-UHFFFAOYSA-N

LogP

2.4451

Topological Polar Surface Area

38.91 Ų

Hydrogen Bond Donor/Acceptor

2 / 2

Complexity

161

Synonyms & References

English

  • 5-Bromo-6-(trifluoromethyl)pyridin-2-amine
  • 5-Bromo-6-trifluoromethylpyridin-2-ylamine
  • 2-Pyridinamine, 5-bromo-6-(trifluoromethyl)-
  • 5-Bromo-6-trifluoromethyl-pyridin-2-ylamine
  • 6-AMINO-3-BROMO-2-(TRIFLUOROMETHYL)PYRIDINE
  • 2-AMINO-5-BROMO-6-(TRIFLUOROMETHYL)PYRIDINE
  • 6-Amino-3-Bromo-2-trifluoromethylpyridine
  • PubChem19285
  • 2-Pyridinamine,5-bromo-6-(trifluoromethyl)-
  • DNDAEASRGBLZCN-UHFFFAOYSA-N
  • 5-bromo-6-trifluoromethylpyridin-2-ylamine
  • 5-Bromo-6-(trifluoromethyl)-2-pyridinamine (ACI)
  • 2-Amino-5-bromo-6-(trifluoromethyl)pyridine
  • 5-Bromo-6-trifluoromethyl-2-aminopyridine
  • DS-11950
  • SCHEMBL1256440
  • AKOS015854971
  • 6-Amino-3-bromo-2-(trifluoromethyl)pyridine
  • DTXSID60672025
  • 2-PYRIDINAMINE, 5-BROMO-6-(TRIFLUOROMETHYL)-
  • CS-W003807
  • 882500-21-2
  • 2-amino-5-bromo-6-trifluoromethyl-pyridine
  • Z1269135569
  • EN300-196248
  • 5-BROMO-6-TRIFLUOROMETHYL-PYRIDIN-2-YLAMINE
  • 5-bromo-6-(trifluoromethyl)pyridin-2-amine
  • MFCD11848010
  • SY008555
  • 2-amino-5-bromo-6-trifluoromethylpyridine
  • J-517139

MDL Number

MFCD11848010

Customs Code

2933399090

FAQ

What regulatory guidelines apply to 5-Bromo-6-(trifluoromethyl)pyridin-2-amine (CAS: 882500-21-2)?

5-Bromo-6-(trifluoromethyl)pyridin-2-amine (CAS: 882500-21-2) falls under the EU's REACH regulations, which require manufacturers and importers to register chemicals and provide safety information. It also adheres to GHS classification for hazardous chemicals, ensuring appropriate labeling and safety data sheets. FDA and EPA have specific requirements for the handling and disposal of this compound to prevent environmental contamination and ensure worker safety.

Are there alternatives to 5-Bromo-6-(trifluoromethyl)pyridin-2-amine (CAS: 882500-21-2) in synthesis?

While 5-Bromo-6-(trifluoromethyl)pyridin-2-amine (CAS: 882500-21-2) is a potent starting material, alternatives include 6-bromo-5-(trifluoromethyl)pyridin-2-amine and other brominated pyridine derivatives. These can be used as substitutes depending on the specific requirements of the synthesis. Common reagents like bromine and trifluoromethylamine are often used in analogous syntheses.

What is the market or research trend for 5-Bromo-6-(trifluoromethyl)pyridin-2-amine (CAS: 882500-21-2)?

The market for 5-Bromo-6-(trifluoromethyl)pyridin-2-amine (CAS: 882500-21-2) is growing due to its applications in pharmaceuticals and materials science. Research trends show an increasing focus on its use in drug discovery and development, particularly in oncology. Market trends indicate rising demand from academic and industrial laboratories, driven by innovations in synthetic chemistry and pharmaceutical research.

How should waste containing 5-Bromo-6-(trifluoromethyl)pyridin-2-amine (CAS: 882500-21-2) be handled?

Waste containing 5-Bromo-6-(trifluoromethyl)pyridin-2-amine (CAS: 882500-21-2) should be collected in a closed, leak-proof container and stored in a well-ventilated area. Incineration is a recommended disposal method to minimize environmental impact. Professional waste disposal services should be used, ensuring compliance with local regulations and environmental protection standards. Proper labeling and documentation of waste management procedures are essential to prevent contamination and ensure safety.

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