Nvp-bbt594 | CAS No. 882405-89-2

Nvp-bbt594

Basic Information

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CAS Number

882405-89-2

Molecular Formula

C28H30F3N7O3

Molecular Weight

569.58 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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CC(=O)NC1=CC(=NC=N1)OC2=CC3=C(C=C2)N(CC3)C(=O)NC4=CC(=C(C=C4)CN5CCN(CC5)C)C(F)(F)F

InChI

InChI=1S/C28H30F3N7O3/c1-18(39)34-25-15-26(33-17-32-25)41-22-5-6-24-19(13-22)7-8-38(24)27(40)35-21-4-3-20(23(14-21)28(29,30)31)16-37-11-9-36(2)10-12-37/h3-6,13-15,17H,7-12,16H2,1-2H3,(H,35,40)(H,32,33,34,39)

InChIKey

VQLNKQZLPGLOSI-UHFFFAOYSA-N

Complexity

904

Synonyms & References

English

BBT594
NVP-BBT594
BBT-594
5-((6-acetamidopyrimidin-4-yl)oxy)-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)indoline-1-carboxamide
5-(6-acetamidopyrimidin-4-yl)oxy-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-2,3-dihydroindole-1-carboxamide
GTPL7584
BCP24855
Q27088113
5-{[6-(acetylamino)pyrimidin-4-yl]oxy}-N-{4-[(4-methylpiperazin-
5-[[6-(Acetylamino)-4-pyrimidinyl]oxy]-2,3-dihydro-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-1H-indole-1-carboxamide (ACI)
BBT 594
NVP-BBT 594
CS-6100
D71160
EX-A2511
AKOS032945083
SCHEMBL12972358
5-[[6-(Acetylamino)-4-pyrimidinyl]oxy]-2,3-dihydro-N-[4-[(4- methyl-1-piperazinyl) methyl]-3-(trifluoromethyl)phenyl]-1H-indole-1-carboxamide
5-{[6-(acetylamino)pyrimidin-4-yl]oxy}-N-{4-[(4-methylpiperazin-1-yl)methyl]-3(trifluoromethyl)phenyl}-2,3-dihydro-1h-indole-1-carboxamide
AC-35538
CHEMBL4799398
BS-17772
882405-89-2
HY-18840
BBT-594; BBT 594; NVP-BBT594; NVP BBT594; NVP BBT-594
VQLNKQZLPGLOSI-UHFFFAOYSA-N
5-(6-acetamidopyrimidin-4-yl)oxy-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-2,3-dihydroindole-1-carboxamide
GLXC-10797

MDL Number

MFCD30533519

FAQ

What is NVP-BBT594 (CAS: 882405-89-2)?

NVP-BBT594 is a small molecule inhibitor of the HIV-1 integrase, which is a key enzyme in the viral life cycle. It has a chemical structure with a specific pharmacophore designed to block the integration of viral DNA into the host genome.

What are the main uses of NVP-BBT594 (CAS: 882405-89-2)?

NVP-BBT594 is primarily used in the research and development of antiretroviral therapies for HIV-1. It is a potent and selective inhibitor of HIV-1 integrase, playing a crucial role in preclinical and clinical studies for potential therapeutic applications.

Is NVP-BBT594 (CAS: 882405-89-2) safe?

NVP-BBT594 is generally considered safe when used under controlled laboratory conditions. However, it should be handled with caution due to its potential toxicity and mutagenic properties. Appropriate protective measures, including gloves and lab coats, should be taken to prevent exposure.

How should NVP-BBT594 (CAS: 882405-89-2) be stored?

NVP-BBT594 should be stored in a tightly sealed container at a temperature below 30°C. Avoid exposure to light and keep away from moisture. The container should be kept in a cool, dry place, away from direct sunlight and heat sources.