2-Methoxy-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine | CAS No. 880361-83-1

2-Methoxy-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine

Basic Information

CAS Number

880361-83-1

Molecular Formula

C8H11N3O

Molecular Weight

165.2 g/mol

AD

Basic Physical Properties

COc1ncc2c(n1)CCNC2

InChI

InChI=1S/C8H11N3O/c1-12-8-10-5-6-4-9-3-2-7(6)11-8/h5,9H,2-4H2,1H3

InChIKey

BXZQEZOMCIZRCS-UHFFFAOYSA-N

LogP

0.13089999999999985

Topological Polar Surface Area

47.040000000000006 Ų

Hydrogen Bond Donor/Acceptor

1 / 4

Safety Information

View Safety Information

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

  • 2-Methoxy-5,6,7,8-tetrahydro-pyrido[4,3-d]pyrimidine
  • 2-methoxy-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine
  • 2-Methoxy-5,6,7,8-tetrahydropyrido[4,3-d]-pyrimidine
  • 3-Aminothietane 1,1-dioxide
  • 2-methoxy-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine
  • 5,6,7,8-Tetrahydro-2-methoxypyrido[4,3-d]pyrimidine (ACI)
  • 2-Methoxy-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine
  • 2-Methoxy-5H,6H,7H,8H-pyrido[4,3-d]pyrimidine

MDL Number

MFCD10697099

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 2-Methoxy-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine (CAS: 880361-83-1)?

2-Methoxy-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine is a crystalline compound with a molecular weight of approximately 211.23 g/mol. It is slightly soluble in water but soluble in common organic solvents like ethanol and DMSO. Chemically, it is stable under normal conditions but reacts with strong acids and bases. It has a melting point of around 105-107°C.

How is 2-Methoxy-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine (CAS: 880361-83-1) typically synthesized?

2-Methoxy-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine is synthesized through a multistep process involving the condensation of methylamine and a pyrimidine derivative. The reaction typically requires a mild base like triethylamine and is carried out in an organic solvent such as DMF. The yield is around 70-80%, and the product is purified by recrystallization from ethanol.

What industries use 2-Methoxy-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine (CAS: 880361-83-1)?

2-Methoxy-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine finds applications in the pharmaceutical industry, particularly in the synthesis of certain antiviral and anti-inflammatory drugs. It is also used in the development of sensors and as a precursor in the production of polymers and semiconductors.

What precautions should be taken when handling 2-Methoxy-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine (CAS: 880361-83-1)?

When handling 2-Methoxy-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine, ensure the use of personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to avoid inhalation. Store it in a cool, dry place away from strong acids and bases. In case of a spill, clean up with appropriate absorbent material and dispose of according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed handling and storage information.

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