2-Methylbenzenesulfonamide

Basic Information

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CAS Number

88-19-7

Molecular Formula

C7H9NO2S

Molecular Weight

171.22 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

156-158 °C

Boiling Point

221 °C

Density

1.2495 (rough estimate)

Water Solubility

Soluble in water (1.6 g/L at 25°C).

Flash Point

178°C

Refractive Index

1.6100 (estimate)

SMILES

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CC1=CC=CC=C1S(=O)(=O)N

InChI

InChI=1S/C7H9NO2S/c1-6-4-2-3-5-7(6)11(8,9)10/h2-5H,1H3,(H2,8,9,10)

InChIKey

YCMLQMDWSXFTIF-UHFFFAOYSA-N

LogP

0.6424200000000001

Topological Polar Surface Area

60.16 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

217

Safety Information

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GHS Hazard Pictograms

H319

H351

Hazard Statement

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H351 Suspected of causing cancer
Carcinogenicity

Synonyms & References

English

2-Methylbenzene-1-sulphonamide
o-Toluenesulfonamide, United States Pharmacopeia (USP) Reference Standard
HSDB 5256
BRN 1102362
TOLUENESULFONAMIDE, O-
4-11-00-00229 (Beilstein Handbook Reference)
DTXSID7021362
EC 201-808-8
LS-7728
2-methylbenzene-sulfonamide
ortho-Toluol-sulfonamid [German]
Tox21_301641
Ketjenflex 9
ortho-Toluenesulphonamide
O-TOLUENESULFONAMIDE [HSDB]
o-Methylbenzenesulfonamide
2-Tolylsulfonamide
NSC 2185
UNII-R81Z6V889P
Benzenesulfonamide, 2-methyl-
TOLUENESULFONAMIDE
Benzenesulfonamide, ar-methyl-
NCGC00255267-01
IEJ
E70309
NSC2185
2-Toluenesulfonamide
methyl-benzenesulphonamide
PD055397
BDBM35999
OTS amide

MDL Number

MFCD00007934

Customs Code

2935009090

FAQ

What is 2-Methylbenzenesulfonamide (CAS: 88-19-7)?

2-Methylbenzenesulfonamide, with the CAS number 88-19-7, is an organic compound that contains a sulfonamide group attached to a methyl-substituted benzene ring. It is a white crystalline solid that is commonly used as an intermediate in chemical synthesis. The chemical formula is C8H10N2O2S, and it exhibits moderate solubility in water and organic solvents. It is known for its stability under normal conditions and is often encountered in pharmaceutical and industrial applications.

What are the main uses of 2-Methylbenzenesulfonamide (CAS: 88-19-7)?

2-Methylbenzenesulfonamide (CAS: 88-19-7) is primarily used as a building block in the synthesis of various pharmaceutical compounds, including drugs and agrochemicals. It also finds applications in the production of dyes, polymers, and other organic materials. In research settings, it serves as a useful reagent for functional group modifications and chemical derivatization. Its versatility makes it a valuable compound in multiple industries.

Is 2-Methylbenzenesulfonamide (CAS: 88-19-7) safe?

2-Methylbenzenesulfonamide (CAS: 88-19-7) is generally considered safe when handled according to proper safety protocols. However, it may cause skin and eye irritation, and inhalation of its dust or vapor can be harmful. It is important to use personal protective equipment, such as gloves and safety goggles, and ensure adequate ventilation when working with this compound. Safety standards recommend following OSHA and EPA guidelines for chemical handling and disposal.

How should 2-Methylbenzenesulfonamide (CAS: 88-19-7) be stored?

2-Methylbenzenesulfonamide (CAS: 88-19-7) should be stored in a cool, dry, and well-ventilated area, away from direct sunlight. It is best kept in a sealed container to prevent moisture absorption and maintain its stability. The recommended storage temperature is between 2-8°C, and it should be protected from humidity and air exposure to avoid degradation. Always store it in a safe location out of reach of children and unauthorized personnel.