Tandospirone | CAS No. 87760-53-0

Tandospirone

Basic Information

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CAS Number

87760-53-0

Molecular Formula

C21H29N5O2

Molecular Weight

383.5 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

112-113.5°

Boiling Point

613.9 °C at 760 mmHg

Density

1.239

Flash Point

613.9 °C at 760 mmHg

Solubility

DMSO: soluble38mg/mL

Refractive Index

1.589

SMILES

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C1CC2CC1C3C2C(=O)N(C3=O)CCCCN4CCN(CC4)C5=NC=CC=N5

InChI

InChI=1S/C21H29N5O2/c27-19-17-15-4-5-16(14-15)18(17)20(28)26(19)9-2-1-8-24-10-12-25(13-11-24)21-22-6-3-7-23-21/h3,6-7,15-18H,1-2,4-5,8-14H2/t15-,16+,17+,18-

InChIKey

CEIJFEGBUDEYSX-FZDBZEDMSA-N

LogP

1.4098999999999986

Topological Polar Surface Area

69.64000000000001 Å²

Hydrogen Bond Donor/Acceptor

0 / 7

Complexity

572

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

Tandospirone
3a,4,7,7a-Hexahydro-2-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-4,7-methano-1H-isoindole-1,3(2H)-dione
[14C]-Tandospirone
SM 3997
SM-3997
(1R*,2S*,3R*,4S*)-N-(4-(4-(2-Pyrimidinyl)-1-piperazinyl)butyl)-2,3-norbornanedicarboximide citrate salt
4,7-Methano-1H-isoindole-1,3(2H)-dione, hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-, (3aα,4β,7β,7aα)- (ZCI)
rel-(3aR,4S,7R,7aS)-Hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-4,7-methano-1H-isoindole-1,3(2H)-dione (ACI)
(3aR,4S,7R,7aS)-2-(4-(4-(pyrimidin-2-yl)piperazin-1-yl)butyl)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione
Tox21_113318
DTXSID6048836
(1S,2R,6S,7R)-4-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione
87760-53-0
(1S,2R,6S,7R)-4-[4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl]-4-aza-tricyclo[5.2.1.0*2,6*]decane-3,5-dione
4,7-METHANO-1H-ISOINDOLE-1,3(2H)-DIONE, HEXAHYDRO-2-(4-(4-(2-PYRIMIDINYL)-1-PIPERAZINYL)BUTYL)-, (3AALPHA,4BETA,7BETA,7AALPHA)-
4,7-METHANO-1H-ISOINDOLE-1,3(2H)-DIONE, HEXAHYDRO-2-(4-(4-(2-PYRIMIDINYL)-1-PIPERAZINYL)BUTYL)-, (3AR,4S,7R,7AS)-REL-
HY-14558
DB12833
Tandospirone (INN)
AC-754
DTXCID3028762
(1S,2R,6S,7R)-4-(4-(4-Pyrimidin-2-yl-piperazin-1-yl)-butyl)-4-aza-tricyclo(5.2.1.0*2,6*)decane-3,5-dione
CAS-87760-53-0
190230I669
(1R,2S,6R,7S)-4-{4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl}-4-azatricyclo[5.2.1.0^{2,6}]decane-3,5-dione
TANDOSPIRONE [WHO-DD]
BDBM50099385
3a,4,7,7a-hexahydro-2-(4-(4-(2-pyrimidinyl)-1-piperazinyl)butyl)-4,7-methano-1H-isoindole-1,3(2H)-dione
AKOS015966978
CHEBI:145673
4,7-Methano-1H-isoindole-1,3(2H)-dione, hexahydro-2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-, (3aalpha,4beta,7beta,7aalpha)-

MDL Number

MFCD00904852

FAQ

What is Tandospirone (CAS: 87760-53-0)?

Tandospirone (CAS: 87760-53-0) is a clinically developed drug used for the treatment of anxiety disorders. It is a selective 5-HT1A receptor partial agonist with high affinity for the 5-HT1A receptor.

What are the main uses of Tandospirone (CAS: 87760-53-0)?

Tandospirone (CAS: 87760-53-0) is primarily used in the treatment of anxiety disorders. It has shown efficacy in managing symptoms of anxiety in clinical trials.

Is Tandospirone (CAS: 87760-53-0) safe?

Tandospirone (CAS: 87760-53-0) is considered safe for use when administered under medical supervision. However, it is important to follow prescribed dosages and heed any warnings or contraindications provided by healthcare professionals.

How should Tandospirone (CAS: 87760-53-0) be stored?

Tandospirone (CAS: 87760-53-0) should be stored at room temperature between 15-30°C (59-86°F), protected from light and moisture. It should be kept in a tightly closed container to prevent loss or degradation of the drug.