5-bromo-3-[(1R)-1-(2,6-dichloro-3-fluoro-phenyl)ethoxy]pyridin-2-amine | CAS No. 877399-00-3

5-bromo-3-[(1R)-1-(2,6-dichloro-3-fluoro-phenyl)ethoxy]pyridin-2-amine

Basic Information

CAS Number

877399-00-3

Molecular Formula

C13H10BrCl2FN2O

Molecular Weight

380.04 g/mol

AD

Basic Physical Properties

Melting Point

107.0 to 111.0 deg-C

Boiling Point

423.4±40.0 °C at 760 mmHg

Density

1.643

Flash Point

209.9±27.3 °C

Vapor Pressure

0.0±1.0 mmHg at 25°C

C[C@H](C1=C(C=CC(=C1Cl)F)Cl)OC2=C(N=CC(=C2)Br)N

InChI

InChI=1S/C13H10BrCl2FN2O/c1-6(11-8(15)2-3-9(17)12(11)16)20-10-4-7(14)5-19-13(10)18/h2-6H,1H3,(H2,18,19)/t6-/m1/s1

InChIKey

URFUZAZEKBBCEY-ZCFIWIBFSA-N

LogP

5.012200000000002

Topological Polar Surface Area

48.14 Ų

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

329

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

  • (R)-5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine
  • (R)-5-Bromo-3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-2-amine
  • (R)-5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)-ethoxy)pyridin-2-amine
  • (R)-5-bromo-3-[1-(2,6-dichloro-3-fluoropehnyl)ethoxy]pyridin-2-amine
  • (R)-5-Bromo-3-[1-(2,6-dichloro-3-fluoro-phenyl)-ethoxy]-pyridin-2-ylamine
  • 3-[(1R)-(2,6- dichloro -3-fluorophenyl) ethoxy]-2- amino -5- bromopyridin
  • 5-bromo-3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-2-Pyridinamine
  • Posaconazole inter-2
  • Pramipexole
  • [5-Bromo-3-[(1R)-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-2-yl]amine
  • QC-4374
  • C13H10BrCl2FN2O
  • URFUZAZEKBBCEY-ZCFIWIBFSA-N
  • BCP26375
  • AX8232207
  • AB0032572
  • B5682
  • X5914
  • ST24020740
  • (R)-5-br
  • 5-Bromo-3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-2-pyridinamine (ACI)
  • [5-Bromo-3-[1(R)-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-2-yl]amine
  • [5-Bromo-3-[[(R)-1-(2,6-dichloro-3-fluorophenyl)ethyl]oxy]pyridin-2-yl]amine

MDL Number

MFCD18207061

Customs Code

2933399090

FAQ

What is 5-bromo-3-[(1R)-1-(2,6-dichloro-3-fluoro-phenyl)ethoxy]pyridin-2-amine (CAS: 877399-00-3)?

5-Bromo-3-[(1R)-1-(2,6-dichloro-3-fluoro-phenyl)ethoxy]pyridin-2-amine (CAS: 877399-00-3) is a brominated, chlorinated, and fluorinated organic compound with a pyridine ring substituted with an amine group and an ethoxy chain. It exhibits moderate solubility in polar solvents and is commonly used as an intermediate in pharmaceutical synthesis. The compound’s molecular formula is C12H9BrCl2F2N2O, and it is characterized by its structural complexity and potential reactivity.

What are the main uses of 5-bromo-3-[(1R)-1-(2,6-dichloro-3-fluoro-phenyl)ethoxy]pyridin-2-amine (CAS: 877399-00-3)?

This compound is primarily utilized in pharmaceutical research for developing drugs targeting neurological and metabolic disorders. Its bromo, chloro, and fluoro substituents make it a valuable intermediate in the synthesis of bioactive molecules. Additionally, it may find applications in agrochemicals and specialty chemical production, though specific commercial uses are limited due to its specialized nature and regulatory constraints.

Is 5-bromo-3-[(1R)-1-(2,6-dichloro-3-fluoro-phenyl)ethoxy]pyridin-2-amine (CAS: 877399-00-3) safe?

Safety precautions are essential when handling 5-bromo-3-[(1R)-1-(2,6-dichloro-3-fluoro-phenyl)ethoxy]pyridin-2-amine (CAS: 877399-00-3). It is classified as a hazardous chemical due to potential toxicity and reactivity. Prolonged exposure may cause irritation, and proper protective equipment (e.g., gloves, goggles) and ventilation are required. Always follow OSHA and EPA guidelines for safe use and disposal.

How should 5-bromo-3-[(1R)-1-(2,6-dichloro-3-fluoro-phenyl)ethoxy]pyridin-2-amine (CAS: 877399-00-3) be stored?

Store 5-bromo-3-[(1R)-1-(2,6-dichloro-3-fluoro-phenyl)ethoxy]pyridin-2-amine (CAS: 877399-00-3) in a sealed, airtight container at room temperature (15-25°C) in a cool, dry, and dark location. Protect from moisture, light, and incompatible materials. Maintain low humidity levels and ensure proper ventilation to prevent degradation or hazardous reactions.

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