Panipenem | CAS No. 87726-17-8

Panipenem

Basic Information

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CAS Number

87726-17-8

Molecular Formula

C15H21N3O4S

Molecular Weight

339.42 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

198-200° (dec)

Boiling Point

555.5 °C at 760 mmHg

Density

1.62

Flash Point

289.7 °C

Refractive Index

1.745

SMILES

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O=C(C(N12)=C(S[C@@H]3CN(C(C)=N)CC3)C[C@]2([H])[C@@H]([C@H](O)C)C1=O)O

InChI

1S/C15H21N3O4S/c1-7(19)12-10-5-11(13(15(21)22)18(10)14(12)20)23-9-3-4-17(6-9)8(2)16/h7,9-10,12,16,19H,3-6H2,1-2H3,(H,21,22)/t7-,9+,10-,12-/m1/s1

InChIKey

TYMABNNERDVXID-DLYFRVTGSA-N

LogP

0.6987699999999997

Topological Polar Surface Area

104.93000000000002 Å²

Hydrogen Bond Donor/Acceptor

3 / 7

Complexity

606

Safety Information

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Toxicity

Approx LD50 in male, female mice (mg/kg): 1700-2200, 1300-1700 i.v. (Kimura)

Synonyms & References

English

Panipenem
D-Panthenol
carbapenemrs-533
cs533
FAROPENEM
Panipenan
PAPM
(5R,6S)-2-[1-Acetamidoylpyrrolidin-3(S)-ylthio]-6-[1(R)-hydroxyethyl]-2-carbapenem-3-carboxylic acid
(5R,6S)-6-[(1R)-1-Hydroxyethyl]-3-[[(3S)-1-(1-iminoethyl)-3-pyrrolidinyl]thio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid (ACI)
1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-3-[[1-(1-iminoethyl)-3-pyrrolidinyl]thio]-7-oxo-, [5R-[3(S*),5α,6α(R*)]]- (ZCI)
CS 533
RS 533

MDL Number

MFCD00865098

FAQ

What regulatory guidelines apply to Panipenem (CAS: 87726-17-8)?

Panipenem (CAS: 87726-17-8) is subject to regulatory guidelines under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), REACH regulations in the European Union, and FDA/EPA guidelines for pharmaceutical and environmental safety. Manufacturers must ensure compliance with these standards for labeling, packaging, and disposal.

Are there alternatives to Panipenem (CAS: 87726-17-8) in synthesis?

Alternatives to Panipenem (CAS: 87726-17-8) in synthesis include other beta-lactam antibiotics such as meropenem and imipenem. These alternatives are used when Panipenem is not viable due to toxicity, stability, or efficacy concerns. Common substituting reagents include various carboxylic acids and carbonyl compounds.

What is the market or research trend for Panipenem (CAS: 87726-17-8)?

The market for Panipenem (CAS: 87726-17-8) is stable, with research focusing on its therapeutic applications in treating resistant bacterial infections. Recent trends include exploring its use in combination therapy and studying its pharmacokinetic properties. Price trends are influenced by production costs and demand in the pharmaceutical industry.

How should waste containing Panipenem (CAS: 87726-17-8) be handled?

Waste containing Panipenem (CAS: 87726-17-8) should be collected in suitable containers, labeled as hazardous waste, and disposed of through professional waste disposal services. Incineration is a common method, but it must comply with local environmental regulations. Environmental protection measures include proper containment to prevent spillage and ensure safe handling and disposal.