2,8-Dimethylimidazo[1,2-a]pyridine-3-carboxylic acid

Basic Information

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CAS Number

874605-59-1

Molecular Formula

C10H10N2O2

Molecular Weight

190.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

122-123°

SMILES

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CC1=CC=CN2C1=NC(=C2C(=O)O)C

InChI

InChI=1S/C10H10N2O2/c1-6-4-3-5-12-8(10(13)14)7(2)11-9(6)12/h3-5H,1-2H3,(H,13,14)

InChIKey

CAFXSRDUIAZBHO-UHFFFAOYSA-N

LogP

1.64934

Topological Polar Surface Area

54.60000000000001 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

244

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

2,8-Dimethylimidazo[1,2-a]pyridine-3-carboxylic acid
2,8-Dimethylimidazo[1,2-a]pyridine-3-carboxylic acid (ACI)
SCHEMBL1340395
2,8-Dimethylimidazo[1,2-a]pyridine-3-carboxylicacid
ZJB60559
STK692718
SY295256
J-507547
874605-59-1
AKOS000345478
ALBB-037120
MFCD00269632
2,8-dimethylimidazo[1,2-a]pyridine-3-carboxylic acid
DTXSID90371236
Imidazo[1,2-a]pyridine-3-carboxylic acid, 2,8-dimethyl-
DC-0729
EN300-1197404
2,8-Dimethyl-Imidazo[1,2-A]Pyridine-3-Carboxylic Acid
CS-0084382

MDL Number

MFCD00269632

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 2,8-Dimethylimidazo[1,2-a]pyridine-3-carboxylic acid (CAS: 874605-59-1)?

2,8-Dimethylimidazo[1,2-a]pyridine-3-carboxylic acid is a crystalline solid with a molecular weight of approximately 206.22 g/mol. It is slightly soluble in water and more soluble in organic solvents. This compound is reactive towards nucleophiles and can undergo esterification and amide formation. It has a melting point of approximately 180-182°C.

How is 2,8-Dimethylimidazo[1,2-a]pyridine-3-carboxylic acid (CAS: 874605-59-1) typically synthesized?

2,8-Dimethylimidazo[1,2-a]pyridine-3-carboxylic acid is typically synthesized through the condensation of 2,8-dimethylimidazo[1,2-a]pyridine-3-carbonitrile with an acid chloride or anhydride, followed by hydrolysis. Commonly used catalysts include acid catalysts such as sulfuric acid. The yield can range from 70% to 90%.

What industries use 2,8-Dimethylimidazo[1,2-a]pyridine-3-carboxylic acid (CAS: 874605-59-1)?

2,8-Dimethylimidazo[1,2-a]pyridine-3-carboxylic acid finds applications in the pharmaceutical industry for the synthesis of certain drugs. It is also used in the production of sensors and as a precursor in the semiconductor industry due to its chemical reactivity and specific functional groups.

What precautions should be taken when handling 2,8-Dimethylimidazo[1,2-a]pyridine-3-carboxylic acid (CAS: 874605-59-1)?

When handling 2,8-Dimethylimidazo[1,2-a]pyridine-3-carboxylic acid, it is important to use appropriate personal protective equipment (PPE), including gloves, safety glasses, and a lab coat. Work should be conducted in a well-ventilated area or fume hood. Spills should be cleaned up immediately using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for specific handling and disposal instructions.