4-Methylbenzoyl chloride

Basic Information

View in Editor

CAS Number

874-60-2

Molecular Formula

C8H7ClO

Molecular Weight

154.6 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

−4-−2 °C

Boiling Point

216°C

Density

1.169 g/mL at 25 °C

Water Solubility

Reacts with water alcohol.

Refractive Index

n20/D 1.553(lit.)

Vapor Pressure

0.55 mmHg ( 20 °C)

SMILES

View in Editor

Cc1ccc(cc1)C(=O)Cl

InChI

InChI=1S/C8H7ClO/c1-6-2-4-7(5-3-6)8(9)10/h2-5H,1H3

InChIKey

NQUVCRCCRXRJCK-UHFFFAOYSA-N

LogP

2.3740200000000007

Topological Polar Surface Area

17.07 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

125

Safety Information

View Safety Information

GHS Hazard Pictograms

H314

Hazard Statement

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Sensitiveness

Moisture Sensitive

Explosive Limit

1.6%, 117°F

Synonyms & References

English

p-Toluoyl chloride
4-Methylbenzoyl chloride
para-toluoyl chloride
p-methylbenzoyl chloride
4-Methylbenzoic acid chloride
4-methylbenzoic chloride
4-methyl-benzoyl chloride
4-Toluoyl chloride
Benzoyl chloride,4-methyl
EINECS 212-864-8
p-Toluic acid chloride
p-Toluyl chloride
Benzoyl chloride, 4-methyl-
4-Methylbenzoylchloride
NQUVCRCCRXRJCK-UHFFFAOYSA-N
092E36PWL4
P-METHYL BENZOYL CHLORIDE
4-toluoylchloride
p-toloyl chloride
rho-toluoyl chloride
p-Toluoyl chloride
4-methyben
4-Methylbenzoyl Chloride
p-Methylbenzoyl chloride
4-Methylbenzoyl chloride (ACI)
p-Toluoyl chloride (6CI, 7CI, 8CI)
4-Methylbenzenecarbonyl chloride
p-Toluenecarbonyl chloride

MDL Number

MFCD00000696

Customs Code

2916399090

FAQ

What is 4-Methylbenzoyl chloride (CAS: 874-60-2)?

4-Methylbenzoyl chloride is an organic compound with the chemical formula C8H7ClO. It is a derivative of benzoic acid, featuring a methyl group attached to the benzene ring. This compound is known for its aromatic structure and reactivity, commonly used in chemical synthesis. It appears as a colorless to pale yellow liquid with a sharp odor and is soluble in organic solvents.

What are the main uses of 4-Methylbenzoyl chloride (CAS: 874-60-2)?

4-Methylbenzoyl chloride is primarily used in pharmaceuticals as an intermediate for drug synthesis. It also finds applications in the production of dyes, coatings, and pesticides. In research, it serves as a versatile reagent for creating various organic compounds. Its utility in chemical reactions makes it valuable in the fragrance and polymer industries as well.

Is 4-Methylbenzoyl chloride (CAS: 874-60-2) safe?

4-Methylbenzoyl chloride is considered toxic and should be handled with care. It may cause eye and skin irritation, and inhalation can be harmful. Safety standards recommend using personal protective equipment such as gloves, goggles, and a fume hood. Proper ventilation and adherence to safety protocols are essential to minimize exposure risks.

How should 4-Methylbenzoyl chloride (CAS: 874-60-2) be stored?

4-Methylbenzoyl chloride should be stored in a cool, dry, and well-ventilated area, away from light. It requires a sealed container to prevent moisture and contamination. Storage conditions should maintain a temperature below 25°C and low humidity to ensure stability. Avoid contact with incompatible materials and keep it in a safe location for handling and disposal.