(2R)-Tetrahydro-2-furancarboxylic acid

Basic Information

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CAS Number

87392-05-0

Molecular Formula

C5H8O3

Molecular Weight

116.12 g/mol

EINECS

627-523-2

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Boiling Point

128-129 °C13 mm Hg

Density

1.209 g/mL at 25 °C

Flash Point

>230 °F

Refractive Index

n20/D 1.46(lit.)

Specific Rotation

+19.6±0.2°(neat) (D/20℃)

SMILES

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OC(=O)[C@H]1CCCO1

InChI

InChI=1S/C5H8O3/c6-5(7)4-2-1-3-8-4/h4H,1-3H2,(H,6,7)/t4-/m1/s1

InChIKey

UJJLJRQIPMGXEZ-SCSAIBSYSA-N

LogP

0.25

pKa

3.60±0.20(Predicted)

Topological Polar Surface Area

46.53 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

99.8

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

Hazard Class

Class 8 Class 8

Synonyms & References

English

(R)-(+)-2-Tetrahydrofuroic acid, 99% (98% ee) 1GR
(R)-(+)-Tetrahydro-2-furoic acid, 99% (98% ee)
(R)-(+)-Tetrahydro-2-furoic acid 99%
(2R)-oxolane-2-carboxylic acid
(R)-(+)-Tetrahydrofuran-2-carboxylic Acid
(R)-(+)-Tetrahydro-2-furoic acid≥ 99% (GC, Chiral purity)
(R)-Tetrahydrofuran-2-carboxylic Acid,99%e.e.
(R)-2-TETRAHYDROFUROIC ACID
(R)-(+)-2-Tetrahydrofuroic acid
(R)-(+)-Tetrahydrofuran-2-carboxylic acid
(R)-(+)-Tetrahydro-2-furoic acid
Faropenem,Fropenem
RCTF
(R)-(+)-2-Carboxy tetrahydrofuroic acid
((R)-(+)-Tetrahydro-2-furoic acid
Faropenem
Fropenem
R-(+)-Tetrahydro-2-furoic acid
(R)-Tetrahydro-2-furoic acid
D-Tetrahydro-furan-2-carboxylic acid
(r)-tetrahydrofuran-2-carboxylic acid
2-Furancarboxylic acid, tetrahydro-, (2R)-
(r)-2-tetrahydrofuroic acid
(S)-2-Tetrahydrofuroic acid
r-tetrahydro-2-furoic acid
(+)-tetrahydro-2-furoic acid
7396HFQ44J
tetrahydro-furan-2-carboxylic acid
(R)-2-Tetrahydrof
(2R)-Tetrahydro-2-furancarboxylic acid (ACI)
2-Furancarboxylic acid, tetrahydro-, (R)- (ZCI)

MDL Number

MFCD00211271

EC Number

627-523-2

Customs Code

29321900

FAQ

What is (2R)-Tetrahydro-2-furancarboxylic acid (CAS: 87392-05-0)?

(2R)-Tetrahydro-2-furancarboxylic acid (CAS: 87392-05-0) is a chiral organic compound with the chemical formula C5H10O3. It is a derivative of tetrahydrofuran, featuring a carboxylic acid group. This compound is known for its stability in organic synthesis and is commonly used as an intermediate in pharmaceutical and chemical research. Its molecular structure includes a five-membered furan ring with hydroxyl and carboxylic acid functionalities, making it versatile for functional group modifications.

What are the main uses of (2R)-Tetrahydro-2-furancarboxylic acid (CAS: 87392-05-0)?

(2R)-Tetrahydro-2-furancarboxylic acid (CAS: 87392-05-0) is primarily used in pharmaceuticals as a building block for drug synthesis, particularly in creating compounds with antioxidant or anti-inflammatory properties. It also serves in industrial applications such as polymer production and solvent systems. In research, it is valued for its role in developing new chemical compounds and studying stereochemistry. Its versatility makes it relevant across chemical, pharmaceutical, and materials science fields.

Is (2R)-Tetrahydro-2-furancarboxylic acid (CAS: 87392-05-0) safe?

(2R)-Tetrahydro-2-furancarboxylic acid (CAS: 87392-05-0) is generally considered safe when handled properly. However, it may cause skin or eye irritation and should be avoided for inhalation or ingestion. Safety precautions include wearing gloves, goggles, and a lab coat, and working in a well-ventilated area. It complies with standard chemical safety regulations, but users should follow OSHA and EPA guidelines to ensure safe handling and minimize exposure risks.

How should (2R)-Tetrahydro-2-furancarboxylic acid (CAS: 87392-05-0) be stored?

(2R)-Tetrahydro-2-furancarboxylic acid (CAS: 87392-05-0) should be stored in a cool, dry place, away from light and heat sources. Keep it in a sealed, airtight container made of glass or HDPE to maintain stability. It is best stored at temperatures below 25°C and humidity levels below 60% to prevent degradation. Ensure proper labeling and store it in a well-ventilated area to avoid inhalation hazards.