2-(Tert-butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline-5-carboxylic acid | CAS No. 872001-50-8
2-(Tert-butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline-5-carboxylic acid
Basic Information
CAS Number
872001-50-8
Molecular Formula
C15H19NO4
Molecular Weight
277.32 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- 2-(tert-Butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline-5-carboxylic acid
- 2-[(2-methylpropan-2-yl)oxycarbonyl]-3,4-dihydro-1H-isoquinoline-5-carboxylic acid
- 2-Boc-1,2,3,4-Tetrahydroisoquinoline-5-Carboxylic Acid
- 3,4-DIHYDRO-1H-ISOQUINOLINE-2,5-DICARBOXYLIC ACID 2-TERT-BUTYL ESTER
- 2-[(tert-butoxy)carbonyl]-1,2,3,4-tetrahydroisoquinoline-5-carboxylic acid
- DTXSID30623367
- 3,4-Dihydro-1H-isoquinoline-2,5-dicarboxylic acid 2-tert-butyl ester
- XJB00150
- 2-(TERT-BUTOXYCARBONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-5-CARBOXYLIC ACID
- DB-031540
- AB13373
- Z1505690921
- 2-BOC-1,2,3,4-TETRAHYDROISOQUINOLINE-5-CARBOXYLIC ACID
- 872001-50-8
- SY157297
- 2-(tert-Butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline-5-carboxylic acid, AldrichCPR
- AKOS022183944
- N-Boc-1,2,3,4-Tetrahydroisoquinoline-5-Carboxylic Acid
- MFCD03094739
- VSVCDLLWJXPCKF-UHFFFAOYSA-N
- EN300-135744
- AS-41717
- SCHEMBL1857142
- 2-(TERT-BUTOXYCARBONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-5-CARBOXYLICACID
- CS-0146217
MDL Number
MFCD03094739
FAQ
What are the physical and chemical properties of 2-(Tert-butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline-5-carboxylic acid (CAS: 872001-50-8)?
2-(Tert-butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline-5-carboxylic acid is a white or off-white crystalline solid with a molecular weight of approximately 323.44 g/mol. It is sparingly soluble in water but soluble in common organic solvents such as methanol and acetonitrile. The compound is moderately reactive, particularly in esterification reactions. It is stable under normal conditions but can hydrolyze in basic conditions.
How is 2-(Tert-butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline-5-carboxylic acid (CAS: 872001-50-8) typically synthesized?
2-(Tert-butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline-5-carboxylic acid is typically synthesized via the protection of 1,2,3,4-tetrahydroisoquinoline-5-carboxylic acid with tert-butoxycarbonyl (Boc) group using di-tert-butyl dicarbonate (Boc2O) in the presence of a base such as triethylamine. The reaction is performed in a polar aprotic solvent like dichloromethane at room temperature.
What industries use 2-(Tert-butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline-5-carboxylic acid (CAS: 872001-50-8)?
2-(Tert-butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline-5-carboxylic acid is primarily used in the pharmaceutical industry, particularly in the synthesis of prodrugs and as a building block for bioactive molecules. It also finds applications in the development of sensors and in the synthesis of certain polymers and semiconductors.
What precautions should be taken when handling 2-(Tert-butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline-5-carboxylic acid (CAS: 872001-50-8)?
When handling 2-(Tert-butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline-5-carboxylic acid, it is important to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight. Spills should be immediately cleaned up with caution, and the Material Safety Data Sheet (MSDS) should be consulted for specific handling and disposal procedures.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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