3-Bromothiophene | CAS No. 872-31-1

Q: What is 3-Bromothiophene (CAS: 872-31-1)?

3-Bromothiophene (CAS: 872-31-1) is a brominated thiophene derivative with the chemical formula C4H3BrS. It is a heterocyclic compound featuring a five-membered ring with a sulfur atom and a bromine substituent at the 3rd carbon position. Known for its aromaticity and reactivity, it is commonly used in organic synthesis. The compound is a liquid at room temperature, has a pungent odor, and is soluble in organic solvents. Its molecular structure makes it valuable in creating complex chemical intermediates.

Q: What are the main uses of 3-Bromothiophene (CAS: 872-31-1)?

3-Bromothiophene (CAS: 872-31-1) is primarily used in pharmaceutical research as a building block for drug development, particularly in compounds targeting fungal and bacterial infections. It also finds applications in industrial chemistry for synthesizing dyes, agrochemicals, and specialty polymers. In organic synthesis, it serves as a key intermediate for creating heterocyclic compounds. Researchers value its role in developing materials with unique electronic properties, such as conductive polymers and sensors.

Q: Is 3-Bromothiophene (CAS: 872-31-1) safe?

3-Bromothiophene (CAS: 872-31-1) requires careful handling due to its potential toxicity. Inhalation or skin contact may cause irritation, while ingestion poses significant health risks. It is classified as a hazardous substance under OSHA and EPA guidelines, necessitating protective measures like gloves, goggles, and ventilation. Long-term exposure may lead to respiratory or dermatological effects. Always follow safety protocols and handle in well-ventilated areas to minimize risks.

Q: How should 3-Bromothiophene (CAS: 872-31-1) be stored?

3-Bromothiophene (CAS: 872-31-1) should be stored in a cool, dry, and dark place, ideally at 2-8°C, to maintain stability. Keep it in a sealed, airtight container to prevent exposure to moisture and air. Avoid contact with incompatible materials like strong oxidizers. Store in a well-ventilated area, away from heat sources, and ensure proper labeling. Maintain controlled humidity levels to prevent degradation.

3-Bromothiophene

Basic Information

View in Editor

CAS Number

872-31-1

Molecular Formula

C4H3BrS

Molecular Weight

163.04 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

<-10°C

Boiling Point

150 °C

Density

1.74 g/mL at 25 °C

Refractive Index

n20/D 1.591(lit.)

SMILES

View in Editor

Brc1ccsc1

InChI

InChI=1S/C4H3BrS/c5-4-1-2-6-3-4/h1-3H

InChIKey

XCMISAPCWHTVNG-UHFFFAOYSA-N

LogP

2.5106

Topological Polar Surface Area

0.0 Å²

Hydrogen Bond Donor/Acceptor

0 / 0

Complexity

46.8

Safety Information

View Safety Information

GHS Hazard Pictograms

H226

H301

H310

H317

H319

H330

H335

Hazard Statement

H226 Flammable liquid and vapor
Flammable liquids

H301 Toxic if swallowed
Acute toxicity, oral

H310 Fatal in contact with skin
Acute toxicity, dermal

H317 May cause an allergic skin reaction
Sensitization, Skin

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H330 Fatal if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1 (3) Class 6.1 (3)

Sensitiveness

Light Sensitive/Stench

Synonyms & References

English

3-Bromothiophene
3-bromo-thiophen
beta-Bromothiophene
thiophene, 3-bromo-
β-bromothiophene
TIMTEC-BB SBB003930
TIMTEC-BB SBB003931
ALPHA-THIENYL BROMIDE
3-THIENYL BROMIDE
3-Bromothiofuran
3-Bromo-thiophene
3-bromonithiophene
3-thienylBr
EINECS 212-821-3
thien-3-yl bromide
Thiophene,3-bromo
3-BROMO THIOPHENE
.beta.-Bromothiophene
bromothiophene(3-)
XCMISAPCWHTVNG-UHFFFAOYSA-N
G818Z74YV0
3-bromothiphene
3-bromthiophene
NSC96612
PubChem5306
KSC448M4H
BIDD:GT0802
SBB003930
TRA0068757
MCUL
3-Thienyl Bromide

MDL Number

MFCD00005464

Customs Code

29349990

FAQ

What is 3-Bromothiophene (CAS: 872-31-1)?

3-Bromothiophene (CAS: 872-31-1) is a brominated thiophene derivative with the chemical formula C4H3BrS. It is a heterocyclic compound featuring a five-membered ring with a sulfur atom and a bromine substituent at the 3rd carbon position. Known for its aromaticity and reactivity, it is commonly used in organic synthesis. The compound is a liquid at room temperature, has a pungent odor, and is soluble in organic solvents. Its molecular structure makes it valuable in creating complex chemical intermediates.

What are the main uses of 3-Bromothiophene (CAS: 872-31-1)?

3-Bromothiophene (CAS: 872-31-1) is primarily used in pharmaceutical research as a building block for drug development, particularly in compounds targeting fungal and bacterial infections. It also finds applications in industrial chemistry for synthesizing dyes, agrochemicals, and specialty polymers. In organic synthesis, it serves as a key intermediate for creating heterocyclic compounds. Researchers value its role in developing materials with unique electronic properties, such as conductive polymers and sensors.

Is 3-Bromothiophene (CAS: 872-31-1) safe?

3-Bromothiophene (CAS: 872-31-1) requires careful handling due to its potential toxicity. Inhalation or skin contact may cause irritation, while ingestion poses significant health risks. It is classified as a hazardous substance under OSHA and EPA guidelines, necessitating protective measures like gloves, goggles, and ventilation. Long-term exposure may lead to respiratory or dermatological effects. Always follow safety protocols and handle in well-ventilated areas to minimize risks.

How should 3-Bromothiophene (CAS: 872-31-1) be stored?

3-Bromothiophene (CAS: 872-31-1) should be stored in a cool, dry, and dark place, ideally at 2-8°C, to maintain stability. Keep it in a sealed, airtight container to prevent exposure to moisture and air. Avoid contact with incompatible materials like strong oxidizers. Store in a well-ventilated area, away from heat sources, and ensure proper labeling. Maintain controlled humidity levels to prevent degradation.