1,4:3,6-Dianhydro-2,5-di-O-nitro-D-glucitol

Basic Information

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CAS Number

87-33-2

Molecular Formula

C6H8N2O8

Molecular Weight

236.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

Powder

Melting Point

700C

Boiling Point

378.59°C (rough estimate)

Density

1.7503 (rough estimate)

Flash Point

186.6°C

Refractive Index

1.5010 (estimate)

Vapor Pressure

0.0±0.8 mmHg at 25°C

Specific Rotation

D20 +135° (alc)

SMILES

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C1C(C2C(O1)C(CO2)O[N+](=O)[O-])O[N+](=O)[O-]

InChI

InChI=1S/C6H8N2O8/c9-7(10)15-3-1-13-6-4(16-8(11)12)2-14-5(3)6/h3-6H,1-2H2/t3-,4+,5-,6-/m1/s1

InChIKey

MOYKHGMNXAOIAT-JGWLITMVSA-N

LogP

log Kow = 1.31

Complexity

268

Safety Information

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Hazard Class

Class 1.1A Class 1.1A

Synonyms & References

English

Isordil
1,4:3, 6-Dianhydro-D-glucitol dinitrate
Isostat
Prestwick_81
EN300-222758
Corosorbide
Sorbide, dinitrate
CAS-87-33-2
KBio2_005779
Isosorbidi dinitras [INN-Latin]
Diluted-isosorbide dinitrate
KBio2_000643
Pharmakon1600-01500358
[(3R,3aS,6S,6aS)-3-nitrooxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] nitrate
KBioGR_000429
SR-05000001658-1
Isosorbide 2,5-dinitrate
Isoket Retard120
Dilatrate SR
Sorate-10
HMS2091P05
Spectrum4_000025
BPBio1_001021
Dilatrate
Sorbitrate (TN)
EureCor
KBio2_003211
ISOSORBIDE DINITRATE COMPONENT OF BIDIL
KBio1_000436
Sorbidi nitras
(3R,3aS,6S,6aS)-6-(nitrooxy)-hexahydrofuro[3,2-b]furan-3-yl nitrate

MDL Number

MFCD00868238

Customs Code

3004909090

FAQ

What is 1,4:3,6-Dianhydro-2,5-di-O-nitro-D-glucitol (CAS: 87-33-2)?

1,4:3,6-Dianhydro-2,5-di-O-nitro-D-glucitol (CAS: 87-33-2) is a dihydroxy compound derived from D-glucitol. It features two nitro groups at the 2 and 5 positions, and its structure includes two anhydro sugar units. This compound is known for its high reactivity and is primarily used in specialized chemical applications.

What are the main uses of 1,4:3,6-Dianhydro-2,5-di-O-nitro-D-glucitol (CAS: 87-33-2)?

1,4:3,6-Dianhydro-2,5-di-O-nitro-D-glucitol (87-33-2) is commonly used in pharmaceutical research as a precursor for drug development. It also finds applications in organic synthesis, particularly in the production of complex molecules. Additionally, it is used in the manufacture of certain specialty chemicals and materials.

Is 1,4:3,6-Dianhydro-2,5-di-O-nitro-D-glucitol (CAS: 87-33-2) safe?

1,4:3,6-Dianhydro-2,5-di-O-nitro-D-glucitol (CAS: 87-33-2) is considered hazardous due to its potential to release toxic fumes upon heating. It should be handled with appropriate personal protective equipment (PPE) and in well-ventilated areas. Safety standards require caution during storage and use to prevent exposure and ensure proper disposal.

How should 1,4:3,6-Dianhydro-2,5-di-O-nitro-D-glucitol (CAS: 87-33-2) be stored?

1,4:3,6-Dianhydro-2,5-di-O-nitro-D-glucitol (CAS: 87-33-2) should be stored in a cool, dry, and well-ventilated place, away from light and heat sources. It is recommended to keep it in a sealed container to prevent moisture absorption and maintain stability. Avoid storage near incompatible substances to ensure safety.