7-Desmethoxy-7-fluoro Elvitegravir | CAS No. 869893-92-5

7-Desmethoxy-7-fluoro Elvitegravir

Basic Information

CAS Number

869893-92-5

Molecular Formula

C22H20ClF2NO4

Molecular Weight

435.85 g/mol

AD

Basic Physical Properties

CC(C)C(CO)N1C=C(C(=O)C2=C1C=C(C(=C2)CC3=C(C(=CC=C3)Cl)F)F)C(=O)O

InChI

InChI=1S/C22H20ClF2NO4/c1-11(2)19(10-27)26-9-15(22(29)30)21(28)14-7-13(17(24)8-18(14)26)6-12-4-3-5-16(23)20(12)25/h3-5,7-9,11,19,27H,6,10H2,1-2H3,(H,29,30)

InChIKey

KIMVXGKCDWQKOQ-UHFFFAOYSA-N

LogP

4.411500000000003

Topological Polar Surface Area

79.53 Ų

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

688

Synonyms & References

English

  • 6-(3-chloro-2-fluorobenzyl)-7-fluoro-1-((S)-1-hydroxymethyl-2-methylpropyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
  • KIMVXGKCDWQKOQ-LJQANCHMSA-N
  • 6-[(3-CHLORO-2-FLUOROPHENYL)METHYL]-7-FLUORO-1-[(2S)-1-HYDROXY-3-METHYLBUTAN-2-YL]-4-OXOQUINOLINE-3-CARBOXYLIC ACID
  • 7-Desmethoxy-7-fluoro Elvitegravir
  • J-519234
  • (S)-6-(3-chloro-2-fluorobenzyl)-7-fluoro-1-(1-hydroxy-3-methylbutan-2-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
  • 6-[(3-Chloro-2-fluorophenyl)methyl]-1-[(25)-1-hydroxy-3-methylbutan-2-yl]-7-fluoro-4-oxoquinoline-3-carboxylic acid
  • DTXSID40730258
  • 6-[(3-Chloro-2-fluorophenyl)methyl]-7-fluoro-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
  • A854813
  • 869893-92-5
  • SCHEMBL1050772
  • 6-[(3-Chloro-2-fluorophenyl)methyl]-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-7-fluoro-4-oxoquinoline-3-carboxylic acid
  • 6-[(3-chloro-2-fluorophenyl)methyl]-7-fluoro-1-[(2S)-1-hydroxy-3-methylbutan-2-yl]-4-oxoquinoline-3-carboxylic acid

MDL Number

MFCD30294860

FAQ

What regulatory guidelines apply to 7-Desmethoxy-7-fluoro Elvitegravir (CAS: 869893-92-5)?

The production, import, and use of 7-Desmethoxy-7-fluoro Elvitegravir (CAS: 869893-92-5) are governed by the REACH regulations in the European Union. In the USA, it is regulated by the FDA and EPA. It is also subject to GHS classification for hazardous substance handling. Special attention should be given to its potential for aquatic toxicity and mutagenicity during disposal.

Are there alternatives to 7-Desmethoxy-7-fluoro Elvitegravir (CAS: 869893-92-5) in synthesis?

In the synthesis of antiretroviral drugs like Elvitegravir, alternative reagents such as fluoroalkyl sulfonates or fluoroalkyl phosphates can be used as substitutes. However, the choice of alternative reagents depends on the specific reaction conditions and the desired product purity.

What is the market or research trend for 7-Desmethoxy-7-fluoro Elvitegravir (CAS: 869893-92-5)?

The market for 7-Desmethoxy-7-fluoro Elvitegravir (CAS: 869893-92-5) is closely tied to its application in antiretroviral therapy, particularly in combination with other HIV medications. Research trends include efforts to improve drug delivery systems and to explore its potential in treating other diseases. Market dynamics suggest increasing demand in developing countries, driven by rising health awareness and improved healthcare infrastructure.

How should waste containing 7-Desmethoxy-7-fluoro Elvitegravir (CAS: 869893-92-5) be handled?

Waste containing 7-Desmethoxy-7-fluoro Elvitegravir (CAS: 869893-92-5) should be collected and disposed of in accordance with local and international waste management regulations. Incineration is a common method, but professional waste disposal services are recommended. Environmental protection measures include minimizing the release of the compound into the environment and ensuring that all waste is treated to prevent contamination of soil and water sources.

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