Corticotropin-releasing factor (human)

Basic Information

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CAS Number

86784-80-7

Molecular Formula

C208H344N60O63S2

Molecular Weight

4757.45 g/mol

Basic Physical Properties

Water Solubility

Soluble to 1.10 mg/ml in water

SMILES

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[H]/N=C(/NCCCC(C(NC(C(NC(C(NC(C(NC(C(NC(C(NC(C(=O)O)C(CC)C)=O)C(CC)C)=O)CCC(=O)O)=O)CC(C)C)=O)CCSC)=O)CCCCN)=O)NC(C(NC(C(NC(C(NC(C(NC(C(NC(C(NC(C(NC(C(NC(C(NC(C(NC(C(NC(C(NC(C(NC(C(NC(C(NC(C(NC(C(C(C)C)NC(C(NC(C(NC(C(NC(C(NC(C(NC(C(NC(C(C(O)C)NC(C(NC(C(NC(C(NC(C(NC(C(C(CC)C)NC(C1N(C(C2N(C(C(NC(C(NC(C(CO)N)=O)CCC(=O)O)=O)CCC(=O)O)=O)CCC2)=O)CCC1)=O)=O)CO)=O)CC(C)C)=O)CC(=O)O)=O)CC(C)C)=O)=O)CC1=CC=CC=C1)=O)CC1N=CNC=1)=O)CC(C)C)=O)CC(C)C)=O)CCCN/C(=N/[H])/N)=O)CCC(=O)O)=O)=O)CC(C)C)=O)CCC(=O)O)=O)CCSC)=O)C)=O)CCCN/C(=N/[H])/N)=O)C)=O)CCC(=O)O)=O)CCC(=O)N)=O)CC(C)C)=O)C)=O)CCC(=O)N)=O)CCC(=O)N)=O)C)=O)CC1N=CNC=1)=O)CO)=O)CC(=O)N)=O)\N

InChI

InChI=1S/C208H343N59O64S2/c1-30-106(20)161(263-198(323)147-49-41-75-266(147)204(329)148-50-42-76-267(148)203(328)132(59-68-158(286)287)246-179(304)126(55-64-154(278)279)235-169(294)117(210)93-268)200(325)260-146(95-270)197(322)253-137(83-102(12)13)189(314)256-144(90-159(288)289)194(319)252-139(85-104(16)17)195(320)265-164(113(27)271)202(327)258-140(86-114-43-34-33-35-44-114)190(315)254-142(88-116-92-222-97-227-116)191(316)251-136(82-101(10)11)188(313)250-135(81-100(8)9)185(310)237-121(48-40-74-225-208(219)220)175(300)241-128(57-66-156(282)283)182(307)261-160(105(18)19)199(324)257-138(84-103(14)15)187(312)242-127(56-65-155(280)281)178(303)244-130(69-77-332-28)172(297)230-109(23)165(290)232-119(46-38-72-223-206(215)216)170(295)228-110(24)166(291)234-125(54-63-153(276)277)177(302)240-124(53-62-151(213)274)180(305)248-133(79-98(4)5)184(309)231-111(25)167(292)233-123(52-61-150(212)273)176(301)239-122(51-60-149(211)272)171(296)229-112(26)168(293)247-141(87-115-91-221-96-226-115)192(317)259-145(94-269)196(321)255-143(89-152(214)275)193(318)238-120(47-39-73-224-207(217)218)174(299)236-118(45-36-37-71-209)173(298)245-131(70-78-333-29)181(306)249-134(80-99(6)7)186(311)243-129(58-67-157(284)285)183(308)262-162(107(21)31-2)201(326)264-163(205(330)331)108(22)32-3/h33-35,43-44,91-92,96-113,117-148,160-164,268-271H,30-32,36-42,45-90,93-95,209-210H2,1-29H3,(H2,211,272)(H2,212,273)(H2,213,274)(H2,214,275)(H,221,226)(H,222,227)(H,228,295)(H,229,296)(H,230,297)(H,231,309)(H,232,290)(H,233,292)(H,234,291)(H,235,294)(H,236,299)(H,237,310)(H,238,318)(H,239,301)(H,240,302)(H,241,300)(H,242,312)(H,243,311)(H,244,303)(H,245,298)(H,246,304)(H,247,293)(H,248,305)(H,249,306)(H,250,313)(H,251,316)(H,252,319)(H,253,322)(H,254,315)(H,255,321)(H,256,314)(H,257,324)(H,258,327)(H,259,317)(H,260,325)(H,261,307)(H,262,308)(H,263,323)(H,264,326)(H,265,320)(H,276,277)(H,278,279)(H,280,281)(H,282,283)(H,284,285)(H,286,287)(H,288,289)(H,330,331)(H4,215,216,223)(H4,217,218,224)(H4,219,220,225)

InChIKey

VXFVFWFSJFSXHN-UHFFFAOYSA-N

LogP

-16.708290000000392

Topological Polar Surface Area

1993.1999999999973 Å²

Hydrogen Bond Donor/Acceptor

76 / 123

Complexity

11700

Synonyms & References

English

CORTICOTROPIN RELEASING FACTOR
CORTICOTROPIN RELEASING FACTOR (CRF), HUMAN, RAT
CORTICOTROPIN RELEASING FACTOR, HUMAN
CORTICOTROPIN RELEASING FACTOR, HUMAN AND RAT
CORTICOTROPIN RELEASING FACTOR HUMAN, RAT
CRF, HUMAN AND RAT
CRF (HUMAN, RAT)
CRH
Corticotropin Releasing Factor human, rat
Corticotropin-releasing factor (human)
Corticotropin-releasing Factor (Human, rat)
CORTICOTROPIN-RELEASING FACTOR(CRF), HUMAN, RAT
CRF (human, rat) Acetate
CRF (human, rat), CRF-41, CRH, Corticoliberin, Corticorelin
Human corticotropin-releasing factor
Human CRF
Corticotropin-releasing factor (human and rat)
Human CRF(1-41)
Human corticotropin-releasing hormone-41
Rat
Rat/human corticotropin-releasing factor

MDL Number

MFCD00213806

Customs Code

2937190000

FAQ

What is Corticotropin-releasing factor (human) (CAS: 86784-80-7)?

Corticotropin-releasing factor (human) (CRF) is a peptide hormone with a molecular formula of C44H66N12O12. It is a key regulator of the hypothalamic-pituitary-adrenal (HPA) axis, influencing stress responses and the release of other hormones.

What are the main uses of Corticotropin-releasing factor (human) (CAS: 86784-80-7)?

Corticotropin-releasing factor (human) is primarily used in research and pharmaceuticals. It is used to study the HPA axis, stress responses, and to develop treatments for stress-related disorders and psychiatric conditions.

Is Corticotropin-releasing factor (human) (CAS: 86784-80-7) safe?

Corticotropin-releasing factor (human) is generally safe when handled and used as directed. However, it should be stored away from children and pets. Protective gloves and safety glasses are recommended when handling to avoid skin contact and inhalation.

How should Corticotropin-releasing factor (human) (CAS: 86784-80-7) be stored?

Corticotropin-releasing factor (human) should be stored at 2-8°C in the refrigerator, protected from light. It should be kept in a tightly sealed container to prevent moisture and contamination.