cis-3-[8-Amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol | CAS No. 867160-71-2

cis-3-[8-Amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol

Basic Information

CAS Number

867160-71-2

Molecular Formula

C26H23N5O

Molecular Weight

421.5 g/mol

AD

Basic Physical Properties

Density

1.39

C[C@]1(C[C@@H](C1)c2n3c(c(ncc3)N)c(n2)c4cc5nc(ccc5cc4)c6ccccc6)O

InChI

InChI=1S/C26H23N5O/c1-26(32)14-19(15-26)25-30-22(23-24(27)28-11-12-31(23)25)18-8-7-17-9-10-20(29-21(17)13-18)16-5-3-2-4-6-16/h2-13,19,32H,14-15H2,1H3,(H2,27,28)

InChIKey

PKCDDUHJAFVJJB-UHFFFAOYSA-N

LogP

4.822100000000004

Topological Polar Surface Area

89.33 Ų

Hydrogen Bond Donor/Acceptor

3 / 6

Complexity

663

Safety Information

View Safety Information

GHS Hazard Pictograms

H302H302

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

Synonyms & References

English

  • Linsitinib
  • OSI-906 (Linsitinib)
  • OSI 906
  • cis-3-[8-Amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol
  • OSI-906AA
  • 3-[8-amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutan-1-ol
  • Cyclobutanol, 3-[8-amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methyl-, cis-
  • Linsitinib (OSI-906, OSI 906AA)
  • Linsitinib(OSI906)
  • OSI-906
  • OSI-906 Linsitinib
  • cis-3-(8-amino-1-(2-phenyl-7-quinolinyl)imidazo(1,5-a)pyrazin-3-yl)-1-methylcyclobutanol
  • cis-3-[8-amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-1-yl]-1-methylcyclobutan-1-ol
  • cis-3-[8-amino-1-(2-phenyl-quinolin-7-yl)-imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol
  • Kinome_3532
  • OSI906
  • 15A52GPT8T
  • MMV676605
  • C26H23N5O
  • 3-[8-amino-1-(2-phenyl-7-quinolinyl)-3-imidazo[1,5-a]pyrazinyl]-1-methyl-1-cyclobutanol
  • cis-3-(8-amino-1-(2-phenyl-7-quinolinyl)imidazo(1,5-a)py

MDL Number

MFCD12912153

FAQ

What regulatory guidelines apply to cis-3-[8-Amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol (CAS: 867160-71-2)?

cis-3-[8-Amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol (CAS: 867160-71-2) is subject to the Globally Harmonized System of Classification and Labeling of Chemicals (GHS), REACH regulations in the EU, and FDA/EPA guidelines for handling and disposal. It is important to consult the latest regulatory documents for specific requirements and to ensure compliance with local and national laws.

Are there alternatives to cis-3-[8-Amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol (CAS: 867160-71-2) in synthesis?

Alternatives to cis-3-[8-Amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol (CAS: 867160-71-2) in synthesis include various quinoline derivatives and imidazopyrazine analogs. Common alternative reagents include phenylquinolines and aminoimidazopyrazines, which can be used as starting materials or intermediate compounds in the synthesis of structurally similar compounds.

What is the market or research trend for cis-3-[8-Amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol (CAS: 867160-71-2)?

The market for cis-3-[8-Amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol (CAS: 867160-71-2) is driven by its potential applications in pharmaceuticals and materials science. Research trends are focused on its biological activity, particularly as a potential drug candidate, and on its use in developing new materials with specific properties. Demand is expected to grow as more applications are discovered and optimized.

How should waste containing cis-3-[8-Amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol (CAS: 867160-71-2) be handled?

Waste containing cis-3-[8-Amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol (CAS: 867160-71-2) should be collected in appropriate containers and handled according to local and national waste management regulations. Incineration or professional waste disposal is recommended to ensure environmental safety. Precautions should be taken to avoid the release of hazardous substances into the environment during handling and disposal processes.

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