Compound Q&A

How is 2-(Chloromethyl)-4-methoxy-3-methylpyridine hydrochloride (CAS: 86604-74-2) typically synthesized?

Answer

2-(Chloromethyl)-4-methoxy-3-methylpyridine hydrochloride (1:1)
This compound is typically synthesized by the reaction of 2-(methylamino)-3-methylpyridine with methyl chloromethyl ether in the presence of a catalytic amount of a base like sodium hydride. The reaction yields a product with high selectivity and good yield.

About

CAS No 86604-74-2
English Name 2-(Chloromethyl)-4-methoxy-3-methylpyridine hydrochloride (1:1)
Molecular Formula C8H11Cl2NO
Molecular Weight 208.08799999999997 g/mol
SMILES Cl.COc1ccnc(CCl)c1C
InChIKey WHAGSNVVBXOIGQ-UHFFFAOYSA-N
Last Updated: 2025-10-13 17:50

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