2-(2,4-Difluorophenyl)-1,3-di(1H-1,2,4-triazol-1-yl)-2-propanol | CAS No. 86386-73-4
2-(2,4-Difluorophenyl)-1,3-di(1H-1,2,4-triazol-1-yl)-2-propanol
Basic Information
CAS Number
86386-73-4
Molecular Formula
C13H12F2N6O
Molecular Weight
306.28 g/mol
AD
Basic Physical Properties
Physical State
Powder
Melting Point
138.0 to 142.0 deg-C
Boiling Point
579.8±60.0 °C at 760 mmHg
Density
1.05
Solubility
DMSO: 5 mg/mL
Vapor Pressure
0.0±1.7 mmHg at 25°C
Safety Information
View Safety InformationHazard Statement
H302
Harmful if swallowed
Acute toxicity, oral
Acute toxicity, oral
H315
Causes skin irritation
Skin corrosion/irritation
Skin corrosion/irritation
H319
Causes serious eye irritation
Serious eye damage/eye irritation
Serious eye damage/eye irritation
Synonyms & References
English
- Fluconazole
- a.-(2,4-Difluorophenyl)-a-(1H-1,2,4,-triazol-1-ylmethyl)-1H-1,2 ,4-triazole-1-ethanol
- 2-(2,4-difluorophenyl)-1,3-di(1H-1,2,4-triazol-1-yl)propan-2-ol
- Fluconazole solution
- FLUCONAZOLE(RG)
- UK-49858
- 2,4-Difluoro-alpha,alpha-1-bis(1H-1,2,4-triazol-1-ylmethyl)benzylalcohol
- diflucan
- Difluean
- Elazor
- Fluconal
- FluMycon
- Flunazol
- Flusol
- triflucan
- UK 49858
- Zoltec
- Fosfluconazole Impurity 1
- 2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol
- alpha-(2,4-Difluorophenyl)-alpha-(1H-1,2,4-triazol-1-ylmethyl)-1H-1,2,4-triazole-1-ethanol
- 2,4-Difluoro-alpha,alpha1-bis(1H-1,2,4-triazol-1-ylmethyl)benzyl alcohol
- [ "" ]
- Biozolene
- Biocanol
- Fluconazol
- Fungata
- Fluconazolum
- Pritenzol
- Flucazol
- Flunizol
- Flukezol
MDL Number
MFCD00274549
Customs Code
2933990090
FAQ
What is 2-(2,4-Difluorophenyl)-1,3-di(1H-1,2,4-triazol-1-yl)-2-propanol (CAS: 86386-73-4)?
2-(2,4-Difluorophenyl)-1,3-di(1H-1,2,4-triazol-1-yl)-2-propanol (CAS: 86386-73-4), also known as fluconazole, is an antifungal medication belonging to the triazole class. It inhibits fungal cell membrane synthesis by targeting ergosterol. The compound has a molecular formula of C10H12F2N4O2 and is commonly used in pharmaceuticals. Its chemical structure includes two triazole rings connected to a difluorophenyl group and a propanol chain, enhancing its antifungal efficacy.
What are the main uses of 2-(2,4-Difluorophenyl)-1,3-di(1H-1,2,4-triazol-1-yl)-2-propanol (CAS: 86386-73-4)?
2-(2,4-Difluorophenyl)-1,3-di(1H-1,2,4-triazol-1-yl)-2-propanol (CAS: 86386-73-4), or fluconazole, is primarily used as an antifungal agent for treating systemic fungal infections. It is effective against Candida species and other opportunistic pathogens. In research, it is studied for its pharmacological properties. Industrially, it is synthesized for pharmaceutical applications. Its broad-spectrum activity makes it a key compound in medical treatments for mycoses.
Is 2-(2,4-Difluorophenyl)-1,3-di(1H-1,2,4-triazol-1-yl)-2-propanol (CAS: 86386-73-4) safe?
2-(2,4-Difluorophenyl)-1,3-di(1H-1,2,4-triazol-1-yl)-2-propanol (CAS: 86386-73-4), known as fluconazole, is generally safe when used as prescribed. However, it may cause side effects like nausea or liver toxicity in rare cases. Proper handling, such as wearing gloves and avoiding inhalation, is recommended during preparation. Safety standards ensure its efficacy and minimal risk, making it a trusted antifungal medication under medical supervision.
How should 2-(2,4-Difluorophenyl)-1,3-di(1H-1,2,4-triazol-1-yl)-2-propanol (CAS: 86386-73-4) be stored?
2-(2,4-Difluorophenyl)-1,3-di(1H-1,2,4-triazol-1-yl)-2-propanol (CAS: 86386-73-4) should be stored in a cool, dry place (15-30°C), away from light and moisture. Keep the container sealed to prevent degradation. Avoid exposure to incompatible substances. Proper storage ensures stability and maintains its antifungal properties for pharmaceutical use.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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