3-{(2R)-3-{(3R)-3-Benzyl-3-[(trimethylhydrazino)carbonyl]-1-piperidinyl}-2-[(2-methylalanyl)amino]-3-oxopropyl}-1H-indole hydrochloride (1:1) | CAS No. 861998-00-7

3-{(2R)-3-{(3R)-3-Benzyl-3-[(trimethylhydrazino)carbonyl]-1-piperidinyl}-2-[(2-methylalanyl)amino]-3-oxopropyl}-1H-indole hydrochloride (1:1)

Basic Information

CAS Number

861998-00-7

Molecular Formula

C31H43ClN6O3

Molecular Weight

583.18 g/mol

AD

Basic Physical Properties

CC(C)(C(=O)N[C@H](Cc1c[nH]c2c1cccc2)C(=O)N3CCC[C@](C3)(Cc4ccccc4)C(=O)N(C)N(C)C)N.Cl

InChI

InChI=1S/C31H42N6O3.ClH/c1-30(2,32)28(39)34-26(18-23-20-33-25-15-10-9-14-24(23)25)27(38)37-17-11-16-31(21-37,29(40)36(5)35(3)4)19-22-12-7-6-8-13-22;/h6-10,12-15,20,26,33H,11,16-19,21,32H2,1-5H3,(H,34,39);1H/t26-,31-;/m1./s1

InChIKey

VFYAEUWJFGTGGO-GHTUPXNNSA-N

LogP

3.140800000000001

Topological Polar Surface Area

114.77 Ų

Hydrogen Bond Donor/Acceptor

4 / 9

Synonyms & References

English

  • UNII-55F75LJQ0V
  • Anamorelin hydrochloride
  • RC 1291 hydrochloride
  • ONO 7643 hydrochloride
  • ONO-7643 hydrochloride
  • SureCN4535148
  • 2-amino-N-[(2R)-1-[(3R)-3-benzyl-3-[dimethylamino(methyl)carbamoyl]piperidin-1-yl]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-methylpropanamide,hydrochloride
  • ANAMORELIN HCL
  • 2-amino-N-[(2R)-1-[(3R)-3-benzyl-3-[dimethylamino(methyl)carbamoyl]piperidin-1-yl]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-2-methylpropanamide
  • hydrochloride
  • RC-1291 hydrochloride

MDL Number

MFCD23098788

FAQ

What are the physical and chemical properties of 3-{(2R)-3-{(3R)-3-Benzyl-3-[(trimethylhydrazino)carbonyl]-1-piperidinyl}-2-[(2-methylalanyl)amino]-3-oxopropyl}-1H-indole hydrochloride (CAS: 861998-00-7)?

This compound is a white crystalline solid with a molecular weight of approximately 594.7 g/mol. It is slightly soluble in water and organic solvents. The compound is known for its high reactivity, particularly in nucleophilic substitution reactions. It is stable under normal storage conditions but should be handled in a fume hood and kept away from strong oxidizers.

How is 3-{(2R)-3-{(3R)-3-Benzyl-3-[(trimethylhydrazino)carbonyl]-1-piperidinyl}-2-[(2-methylalanyl)amino]-3-oxopropyl}-1H-indole hydrochloride (CAS: 861998-00-7) typically synthesized?

This compound is synthesized via a multi-step process involving condensation reactions and hydrazine derivatization. Commonly, it involves the synthesis of the key intermediate, followed by coupling reactions. The synthesis typically requires the use of catalysts such as palladium and ligands to achieve high selectivity and yield. Detailed protocols can be found in specific research papers and chemical literature.

What industries use 3-{(2R)-3-{(3R)-3-Benzyl-3-[(trimethylhydrazino)carbonyl]-1-piperidinyl}-2-[(2-methylalanyl)amino]-3-oxopropyl}-1H-indole hydrochloride (CAS: 861998-00-7)?

This compound is primarily used in the pharmaceutical industry for the development of novel therapeutic agents. It may also find applications in sensors and semiconductors due to its specific chemical functionalities. The compound's unique chemical structure makes it suitable for targeted drug delivery and other specialized applications.

What precautions should be taken when handling 3-{(2R)-3-{(3R)-3-Benzyl-3-[(trimethylhydrazino)carbonyl]-1-piperidinyl}-2-[(2-methylalanyl)amino]-3-oxopropyl}-1H-indole hydrochloride (CAS: 861998-00-7)?

Handling this compound requires strict safety measures. Wear appropriate personal protective equipment (PPE) including gloves, goggles, and a lab coat. Work in a well-ventilated area or fume hood to minimize exposure. Store the compound in a cool, dry place away from direct sunlight and strong oxidizers. In case of spill, neutralize the spill with appropriate chemicals and dispose of according to local regulations. Always refer to the Material Safety Data Sheet (MSDS) for detailed safety information.

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