GRF (1-29) amide (human) acetate salt H-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2 acetate salt

Basic Information

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CAS Number

86168-78-7

Molecular Formula

C149H246N44O42S

Molecular Weight

3357.88 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Specific Rotation

D20 -63.1° (c = 1 in 30% acetic acid)

SMILES

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CC[C@@H]([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](N)CC1=CC=C(O)C=C1)=O)C)=O)CC(O)=O)=O)C)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CCCNC(N)=N)=O)CO)=O)CCSC)=O)[C@H](CC)C)=O)CC(O)=O)=O)CCC(N)=O)=O)CC(C)C)=O)CC(C)C)=O)CCCCN)=O)CCCNC(N)=N)=O)C)=O)CO)=O)CC(C)C)=O)CCC(N)=O)=O)=O)CC(C)C)=O)C(C)C)=O)CCCCN)=O)CCCNC(N)=N)=O)CC2=CC=C(O)C=C2)=O)CO)=O)CC(N)=O)=O)[C@H](O)C)=O)CC3=CC=CC=C3)=O)C

InChI

InChIKey

WGWPRVFKDLAUQJ-MITYVQBRSA-N

LogP

-14.349190000000068

Topological Polar Surface Area

1446.8999999999992 Å²

Hydrogen Bond Donor/Acceptor

62 / 86

Complexity

7640

Synonyms & References

English

sermorelin
GRF (1-29) amide (human)
H-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2
growth hormone releasing factor*fragment 1-29 ami
Sermorelin Aceta
Sermorelin Acetate
SERMORELIN, GROWTH HORMONE RELEASING FACTOR FRAGMENT 1-40 AMIDE
GHRH (1-29)
Growth Hormone Releasing Factor Fragment 1-29 amide human
Sermorelin [INN:BAN]
Somatoliberin (human pancreatic islet), 29-L-argininamide-30-de-L-glutamine-31-de-L-glutamine-32-deglycine-33-de-L-glutamic acid-34-de-L-serine-35-de-L-asparagine-36-de-L-glutamine-37-de-L-glutamic acid-38-de-L-arginine-39-deglycine-40-de-L-alanine-41-de-L-arginine-42-de-L-alanine-43-de-L-argininyl-44-de-L-leucinamide
Sermorelina
Sermorelina [Spanish]
Sermoreline
Sermoreline [French]
Sermorelinum
Sermorelinum [Latin]
UNII-89243S03TE

MDL Number

MFCD00076559

FAQ

What is GRF (1-29) amide (human) acetate salt (CAS: 86168-78-7)?

GRF (1-29) amide (human) acetate salt (CAS: 86168-78-7) is a synthetic peptide compound derived from the human growth hormone-releasing factor (GRF). Its chemical structure consists of the amino acid sequence H-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2, modified as an acetate salt. This compound is commonly used in research and pharmaceutical applications for its role in stimulating growth hormone release.

What are the main uses of GRF (1-29) amide (human) acetate salt (CAS: 86168-78-7)?

GRF (1-29) amide (human) acetate salt (CAS: 86168-78-7) is primarily utilized in pharmaceutical research for studying growth hormone regulation. It also serves as a tool in medical studies related to endocrinology and may be involved in therapeutic development for conditions like growth hormone deficiency. Additionally, it is used in biochemical research to investigate peptide mechanisms and receptor interactions.

Is GRF (1-29) amide (human) acetate salt (CAS: 86168-78-7) safe?

GRF (1-29) amide (human) acetate salt (CAS: 86168-78-7) is generally considered safe when handled according to standard laboratory protocols. However, as a peptide compound, it may cause irritation if inhaled or contacted with skin. Safety measures include wearing gloves, goggles, and a lab coat, and following disposal guidelines to prevent environmental contamination. Always refer to safety data sheets for specific precautions.

How should GRF (1-29) amide (human) acetate salt (CAS: 86168-78-7) be stored?

GRF (1-29) amide (human) acetate salt (CAS: 86168-78-7) should be stored in a cool, dry place, ideally refrigerated at 2-8°C, to maintain stability. Protect from light and moisture by using airtight containers. Ensure storage is in a well-ventilated area and keep away from incompatible substances to preserve its integrity and efficacy.