(R)-(-)-3-Hydroxytetrahydrofuran

Basic Information

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CAS Number

86087-24-3

Molecular Formula

C4H8O2

Molecular Weight

88.11 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

Colorless to Yellow Liquid

Boiling Point

80°C/15mmHg

Density

1.097 g/mL at 25 °C

Refractive Index

n20/D 1.45(lit.)

Specific Rotation

-18.5 º (c=2 MeOH)

SMILES

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C1COCC1O

InChI

InChI=1S/C4H8O2/c5-4-1-2-6-3-4/h4-5H,1-3H2/t4-/m1/s1

InChIKey

XDPCNPCKDGQBAN-SCSAIBSYSA-N

LogP

-0.23239999999999994

Topological Polar Surface Area

29.46 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

44.8

Safety Information

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Hazard Statement

H227 Combustible liquid
Flammable liquids

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Synonyms & References

English

(R)-(-)-3-Hydroxytetrahydrofuran
(R)-3-Hydroxy Tetrahydrofuran
R-(-)-3-Hydroxytetrahydrofuran
(R)-Tetrahydrofuran-3-ol
(R)-(?)-3-Hydroxytetrahydrofuran
(R)-(-)-Tetrahydro-3-furanol
3-Furanol,tetrahydro-, (R)-
(-)-3-Hydroxytetrahydrofuran
(3R)-3-Hydroxytetrahydrofuran
(R)-(-)-3-Hydroxy-tetrahydro-furan
(R)-(-)-Tetrahydrofuran-3-ol
(R)-3-Hydroxy-tetrahydro-furan
(R)-Tetrahydro-3-furanol
3(R)-Hydroxytetrahydrofuran
(R)-3-Hydroxytetrahydrofuran
(3R)-oxolan-3-ol
(3R)-Tetrahydrofuran-3-ol
3-Furanol, tetrahydro-, (3R)-
(R)-(+)-3-Hydroxytetrahydrofuran
(R)-Tetrahydro-furan-3-ol
PubChem7071
Tetrahydrofuran-3alpha-ol
S)-(-)-3-Hydoxy tetahydro tetrahydro furan
(3R)-tetrahydro-3-furanol
KSC496K1N
(R)-3-hydroxy-tetrahydrofuran
XDPCNPCKDGQBAN-SCSAIBSYSA-N
(-)-(r)
EN300-94223
3-Furanol, tetrahydro-, (R)-
AKOS005256250

MDL Number

MFCD00067101

FAQ

What is (R)-(-)-3-Hydroxytetrahydrofuran (CAS: 86087-24-3)?

(R)-(-)-3-Hydroxytetrahydrofuran is a chiral organic compound with the chemical formula C5H10O2. It is a derivative of tetrahydrofuran, featuring a hydroxyl group at the 3-position and a specific stereochemistry (R) with a (-) optical rotation. This compound is known for its polar nature and is commonly used in organic synthesis and as a precursor for various pharmaceutical and chemical applications.

What are the main uses of (R)-(-)-3-Hydroxytetrahydrofuran (CAS: 86087-24-3)?

(R)-(-)-3-Hydroxytetrahydrofuran finds applications in pharmaceutical research, particularly in the synthesis of chiral drugs and bioactive molecules. It is also used in the production of polymers, solvents, and as an intermediate in the manufacture of fine chemicals. Its utility extends to research in organic chemistry and medicinal chemistry for developing new therapeutic agents.

Is (R)-(-)-3-Hydroxytetrahydrofuran (CAS: 86087-24-3) safe?

Safety of (R)-(-)-3-Hydroxytetrahydrofuran depends on its handling and exposure conditions. It is generally considered safe when used in controlled environments, but proper protective measures such as gloves and ventilation should be taken. Safety data sheets (SDS) indicate it is non-toxic in low concentrations, though its handling should follow standard chemical safety protocols to ensure user and environmental safety.

How should (R)-(-)-3-Hydroxytetrahydrofuran (CAS: 86087-24-3) be stored?

(R)-(-)-3-Hydroxytetrahydrofuran should be stored in a cool, dry, and well-ventilated place, away from light and moisture. It is typically kept in sealed containers made of glass or high-density polyethylene (HDPE) to prevent degradation. Storage conditions should maintain a temperature below 25°C and ensure humidity levels are controlled to preserve its chemical stability and purity.