2-Methyl-2-propanyl (3R)-3-[(dimethylamino)methyl]-1-pyrrolidinecarboxylate | CAS No. 859027-48-8

2-Methyl-2-propanyl (3R)-3-[(dimethylamino)methyl]-1-pyrrolidinecarboxylate

Basic Information

CAS Number

859027-48-8

Molecular Formula

C12H24N2O2

Molecular Weight

228.34 g/mol

AD

Basic Physical Properties

CC(C)(C)OC(=O)N1CCC(C1)CN(C)C

InChI

InChI=1S/C12H24N2O2/c1-12(2,3)16-11(15)14-7-6-10(9-14)8-13(4)5/h10H,6-9H2,1-5H3/t10-/m1/s1

InChIKey

SVFCKPUIJBZBQS-SNVBAGLBSA-N

LogP

1.8049999999999997

Topological Polar Surface Area

32.78 Ų

Hydrogen Bond Donor/Acceptor

0 / 4

Complexity

246

Synonyms & References

English

  • AMY32693
  • (R)-tert-butyl 3-((dimethylamino)methyl)pyrrolidine-1-carboxylate
  • DTXSID20647517
  • (R)-1-N-Boc-3-[(Dimethylamino)methyl]pyrrolidine
  • (R)-1-Boc-3-((dimethylamino)methyl)pyrrolidine
  • I11638
  • AKOS015850673
  • J-502284
  • 3-Dimethylaminomethyl-pyrrolidine-1-carboylic acid tert-butyl ester
  • R-1-BOC-3-DIMETHYLAMINOMETHYL-PYRROLIDINE
  • 859027-48-8
  • AC-2237
  • SCHEMBL3568388
  • tert-Butyl-(3R)-3-[(dimethylamino)methyl]pyrrolidin-1-carboxylat
  • CS-0001897
  • AKOS015910632
  • tert-butyl (3R)-3-[(dimethylamino)methyl]pyrrolidine-1-carboxylate
  • A841484
  • (R)-1-Boc-3-((Dimethylamino)methyl)pyrrolidine
  • (R)-1-tert-Butoxycarbonyl-3-((dimethylamino)methyl)pyrrolidine

MDL Number

MFCD08275941

FAQ

What are the physical and chemical properties of 2-Methyl-2-propanyl (3R)-3-[(dimethylamino)methyl]-1-pyrrolidinecarboxylate (CAS: 859027-48-8)?

2-Methyl-2-propanyl (3R)-3-[(dimethylamino)methyl]-1-pyrrolidinecarboxylate is a colorless liquid with a molecular weight of 243.4 g/mol. It has a high solubility in organic solvents such as ethanol and acetone but is only slightly soluble in water. The compound is known for its high reactivity, particularly towards nucleophiles and acids.

How is 2-Methyl-2-proanyl (3R)-3-[(dimethylamino)methyl]-1-pyrrolidinecarboxylate (CAS: 859027-48-8) typically synthesized?

2-Methyl-2-proanyl (3R)-3-[(dimethylamino)methyl]-1-pyrrolidinecarboxylate is synthesized via a multistep process involving the protection of a pyrrolidine ring, followed by a nucleophilic substitution reaction with dimethylaminomethyl compound. The reaction is catalyzed by a metal ion, and the process yields a high purity product with good selectivity.

What industries use 2-Methyl-2-proanyl (3R)-3-[(dimethylamino)methyl]-1-pyrrolidinecarboxylate (CAS: 859027-48-8)?

This compound is primarily used in the pharmaceutical industry as a precursor in the synthesis of drug candidates. It is also utilized in the polymer industry for the modification of polymers to improve their properties. Additionally, it has applications in semiconductors for specific chemical processes and in sensors for detecting certain analytes.

What precautions should be taken when handling 2-Methyl-2-proanyl (3R)-3-[(dimethylamino)methyl]-1-pyrrolidinecarboxylate (CAS: 859027-48-8)?

When handling 2-Methyl-2-proanyl (3R)-3-[(dimethylamino)methyl]-1-pyrrolidinecarboxylate, ensure the use of personal protective equipment (PPE) including gloves, a lab coat, and safety goggles. Work in a well-ventilated area or fume hood to avoid inhalation. Follow standard laboratory safety procedures, and keep the substance away from heat and ignition sources. In case of a spill, neutralize it with an appropriate chemical and dispose of according to local regulations. Always refer to the Safety Data Sheet (SDS) for specific handling instructions.

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