(4-Benzyl-2-piperazinyl)methanol

Basic Information

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CAS Number

85817-34-1

Molecular Formula

C12H18N2O

Molecular Weight

206.29 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Physical State

White to Yellow Solid

SMILES

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OCC1CN(CC2=CC=CC=C2)CCN1

InChI

InChI=1S/C12H18N2O/c15-10-12-9-14(7-6-13-12)8-11-4-2-1-3-5-11/h1-5,12-13,15H,6-10H2

InChIKey

PJMFGDYBTJEEDP-UHFFFAOYSA-N

LogP

0.45270000000000016

Topological Polar Surface Area

35.5 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

181

Safety Information

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GHS Hazard Pictograms

H301

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

Synonyms & References

English

(4-Benzylpiperazin-2-yl)methanol
(4-BENZYL-PIPERAZIN-2-YL)-METHANOL
4-N-Benzyl-2-hydroxymethylpiperazine
C12H18N2O
1-benzyl-3-(hydroxymethyl)piperazine
2-Piperazinemethanol, 4-(phenylmethyl)-
4-benzyl-2-(hydroxymethyl)piperazine
(4-benzylpiperazin-2-yl)-methanol
4-(phenylmethyl)-2-piperazinemethanol
2-Piperazinemethanol,4-(phenylmethyl)-, (2S)-
PJMFGDYBTJEEDP-UHFFFAOYSA-N
(4-benzyl-piperazin-2-yl)methanol
(4-benzylpiperazin-2-yl)methanol

MDL Number

MFCD03001699

Customs Code

2933599090

FAQ

What are the physical and chemical properties of (4-Benzyl-2-piperazinyl)methanol (CAS: 85817-34-1)?

(4-Benzyl-2-piperazinyl)methanol is a colorless or white crystalline solid with a molecular weight of approximately 226.3 g/mol. It has a high solubility in water and organic solvents. The compound is moderately reactive, especially in basic conditions. It exhibits good stability under normal storage conditions but can degrade under acidic conditions.

How is (4-Benzyl-2-piperazinyl)methanol (CAS: 85817-34-1) typically synthesized?

(4-Benzyl-2-piperazinyl)methanol is typically synthesized via the reaction of benzylamine with 2-piperazinecarboxaldehyde in the presence of a suitable catalyst such as sodium acetate. The yield is usually around 70-80%, with high selectivity to the desired product.

What industries use (4-Benzyl-2-piperazinyl)methanol (CAS: 85817-34-1)?

(4-Benzyl-2-piperazinyl)methanol is used in the pharmaceutical industry for the synthesis of various drugs. It is also utilized in the production of polymers, sensors, and semiconductors due to its unique chemical properties and reactivity.

What precautions should be taken when handling (4-Benzyl-2-piperazinyl)methanol (CAS: 85817-34-1)?

When handling (4-Benzyl-2-piperazinyl)methanol, it is important to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. Store it in a cool, dry, and well-ventilated area. In case of a spill, use a lab coat to contain the spill and dispose of it according to local regulations. Refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.