4-{3-Chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxy-6-quinolinecarboxamide methanesulfonate (1:1) | CAS No. 857890-39-2

4-{3-Chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxy-6-quinolinecarboxamide methanesulfonate (1:1)

Basic Information

CAS Number

857890-39-2

Molecular Formula

C22H23ClN4O7S

Molecular Weight

522.97 g/mol

AD

Basic Physical Properties

COC1=CC2=NC=CC(=C2C=C1C(=O)N)OC3=CC(=C(C=C3)NC(=O)NC4CC4)Cl.CS(=O)(=O)O

InChI

InChI=1S/C21H19ClN4O4.CH4O3S/c1-29-19-10-17-13(9-14(19)20(23)27)18(6-7-24-17)30-12-4-5-16(15(22)8-12)26-21(28)25-11-2-3-11;1-5(2,3)4/h4-11H,2-3H2,1H3,(H2,23,27)(H2,25,26,28);1H3,(H,2,3,4)

InChIKey

HWLFIUUAYLEFCT-UHFFFAOYSA-N

LogP

3.5759000000000016

Topological Polar Surface Area

169.94 Ų

Hydrogen Bond Donor/Acceptor

5 / 11

Complexity

727

Safety Information

View Safety Information

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral
H315 Causes skin irritation
Skin corrosion/irritation
H319 Causes serious eye irritation
Serious eye damage/eye irritation
H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

  • 4-(3-Chloro-4-(N'-cyclopropylureido)phenoxy)7-methoxyquinoline-6-carboxamide Mesylate
  • Multi-Kinase Inhibitor E7080 Mesylate
  • 6-Quinolinecarboxamide, 4-(3-chloro-4-(((cyclopropylamino)carbonyl)amino)phenoxy)- 7-methoxy-, methanesulfonate (1:1)
  • Lenvatinib (mesylate)
  • A900902
  • lenvatinibMesylate
  • 4-[3-Chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide monomethanesulfonate
  • 3J78384F61
  • 6-carbamoyl-4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinolin-1-ium methanesulfonate
  • E7080Mesylate
  • LENVATINIB MESYLATE
  • AC-30100
  • 857890-39-2
  • Lenvatinib methanesulfonate
  • methanesulfonic acid--4-{3-chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxyquinoline-6-carboxamide (1/1)
  • BCP11858
  • Lenvima (TN)
  • 4-(3-Chloro-4-(3-cyclopropylureido)phenoxy)-7-methoxyquinoline-6-carboxamide methanesulfonate
  • DS-19245
  • UNII-3J78384F61
  • N-(4-((6-Carbamoyl-7-methoxyquinolin-4-yl)oxy)-2-chlorophenyl)-N'-cyclopropylurea monomethanesulfonate
  • Lenvatinib mesilate
  • CHEMBL2105704
  • Q27158839
  • DTXCID90157572
  • CCG-269873
  • Lenvatinib mesylate (USAN)
  • AKOS030632716
  • Lenvatinib mesilate (JAN)
  • CS-0030963
  • 1ST164749S

MDL Number

MFCD18633219

FAQ

What is 4-{3-Chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxy-6-quinolinecarboxamide methanesulfonate (1:1) (CAS: 857890-39-2)?

4-{3-Chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxy-6-quinolinecarboxamide methanesulfonate (1:1) is a chemical compound with the CAS number 857890-39-2. It contains a quinolinecarboxamide core with additional substituents, including a methoxy group and a methanesulfonate group. This compound is known for its complex molecular structure and is often used in specialized chemical applications due to its functional groups and potential biological activity.

What are the main uses of 4-{3-Chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxy-6-quinolinecarboxamide methanesulfonate (1:1) (CAS: 857890-39-2)?

This compound is primarily used in pharmaceutical research as a potential inhibitor or modulator of specific enzymes or biological pathways. It also finds applications in chemical synthesis and as a reagent in organic chemistry due to its structural features. Its use in industrial and food sectors is limited, but it may be employed in specialized research contexts for drug development and molecular studies.

Is 4-{3-Chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxy-6-quinolinecarboxamide methanesulfonate (1:1) (CAS: 857890-39-2) safe?

The safety of 4-{3-Chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxy-6-quinolinecarboxamide methanesulfonate (1:1) depends on its handling and application. As a research compound, it is generally considered safe when used in controlled laboratory environments with appropriate protective measures. However, it should be handled with care, following standard chemical safety protocols to avoid exposure and ensure safe disposal.

How should 4-{3-Chloro-4-[(cyclopropylcarbamoyl)amino]phenoxy}-7-methoxy-6-quinolinecarboxamide methanesulfonate (1:1) (CAS: 857890-39-2) be stored?

This compound should be stored in a cool, dry, and dark place to maintain its stability. It is recommended to keep it in a sealed container, away from moisture and light, at a temperature below 25°C. Avoid exposure to air and ensure proper ventilation when handling. Storage conditions should be controlled to prevent degradation and maintain chemical integrity.

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