Tedizolid phosphate

Basic Information

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CAS Number

856867-55-5

Molecular Formula

C17H16FN6O6P

Molecular Weight

450.32 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Insecticides

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

SMILES

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Cn1nnc(n1)c2ccc(cn2)c3ccc(cc3F)N4C[C@H](COP(=O)(O)O)OC4=O

InChI

InChI=1S/C17H16FN6O6P/c1-23-21-16(20-22-23)15-5-2-10(7-19-15)13-4-3-11(6-14(13)18)24-8-12(30-17(24)25)9-29-31(26,27)28/h2-7,12H,8-9H2,1H3,(H2,26,27,28)/t12-/m1/s1

InChIKey

QCGUSIANLFXSGE-GFCCVEGCSA-N

LogP

1.5126999999999997

Topological Polar Surface Area

152.79 Å²

Hydrogen Bond Donor/Acceptor

2 / 12

Complexity

702

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

tedizolid phosphate
-3-(4-(2-(2-Methyltetrazol-5-yl)pyridine-5-yl)-3-fluorophenyl)-5-hydroxyMethyl oxazolidin-2-one phosphate
(5R)-3-[3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-[(phosphonooxy)methyl]-2-oxazolidinone
(R) -3-(4-(2-(2-Methyltetrazol-5-yl)pyridine-5-yl)-3-fluorophenyl)-5-hydroxyMethyl oxazolidin-2-one phosphate
(R)-(3-(3-Fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-2-oxooxazolidin-5-yl)methyl dihydrogen phosphate
[(5R)-3-[3-fluoro-4-[6-(2-methyltetrazol-5-yl)pyridin-3-yl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl dihydrogen phosphate
TR-701 FA
DA7157
Torezolid phosphate
TR700
UNII-O7DRJ6R4DW
Tedizolid (phosphate)
Sivextro
O7DRJ6R4DW
NE63553
[(5R)-3-{3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl]phenyl}-2-oxo-1,3-oxazolidin-5-yl]methyl dihydrogen phosphate
(R)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyloxazolidin
tedizolid-phosphate
(R)-3-(4-(2-(2-methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyloxazolidin-2-one dihydrogenphosphate
[(5R)-3-[3-fluoro-4-[6-(2-methyltetrazol-5-yl)pyridin-3-yl]phen
Tedizolid phosphate

MDL Number

MFCD28098176

FAQ

What is Tedizolid phosphate (CAS: 856867-55-5)?

Tedizolid phosphate is an antibiotic compound used in the treatment of bacterial infections. It has the chemical formula C18H24N4O10PS2 and is known for its activity against gram-positive bacteria. It is a prodrug that converts to tedizolid in the body, which inhibits protein synthesis by targeting the bacterial ribosome. Tedizolid phosphate is commonly used in pharmaceutical formulations for its broad-spectrum efficacy and favorable pharmacokinetic properties.

What are the main uses of Tedizolid phosphate (CAS: 856867-55-5)?

Tedizolid phosphate is primarily used in pharmaceutical applications to treat skin and soft tissue infections caused by susceptible bacteria. It is also effective against certain respiratory tract infections. Due to its mechanism of action, it is particularly useful in cases where other antibiotics may not be suitable. Its use extends to research and development in the field of antimicrobial therapy and drug formulation.

Is Tedizolid phosphate (CAS: 856867-55-5) safe?

Tedizolid phosphate is generally considered safe when used as directed, but it should be handled with appropriate precautions. It has a favorable safety profile with minimal toxicity, though adverse effects such as liver enzyme elevation may occur. Safety standards recommend following prescribed dosages and consulting healthcare professionals. Protective measures include proper personal protective equipment (PPE) during handling and storage.

How should Tedizolid phosphate (CAS: 856867-55-5) be stored?

Tedizolid phosphate should be stored in a cool, dry place away from direct light. It is typically kept at a temperature between 15°C to 25°C (59°F to 77°F) and in airtight containers to prevent moisture exposure. Proper storage ensures stability and maintains the compound's potency. Avoiding extreme temperatures and humidity is essential to preserve its chemical integrity and effectiveness.