2-Chloro-3,5-diiodopyridine

Basic Information

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CAS Number

856169-60-3

Molecular Formula

C5H2ClI2N

Molecular Weight

365.34 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

71-74°C

Boiling Point

351.3°C at 760 mmHg

SMILES

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Ic1cnc(c(c1)I)Cl

InChI

InChI=1S/C5H2ClI2N/c6-5-4(8)1-3(7)2-9-5/h1-2H

InChIKey

FVCKBKBSDFLXGY-UHFFFAOYSA-N

LogP

2.9442000000000004

Topological Polar Surface Area

12.89 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

101

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Sensitiveness

Light Sensitive

Synonyms & References

English

2-Chloro-3,5-diiodopyridine
Pyridine,2-chloro-3,5-diiodo-
FVCKBKBSDFLXGY-UHFFFAOYSA-N
STK893387
3310AC
BBL020697
FCH1325741
VP13878
OR310200
AX8072698
ST24040276
H8385

MDL Number

MFCD04966987

FAQ

What are the physical and chemical properties of 2-Chloro-3,5-diiodopyridine (CAS: 856169-60-3)?

2-Chloro-3,5-diiodopyridine is a crystalline solid with a molecular weight of approximately 433.9 g/mol. It has low water solubility and moderate solubility in organic solvents like DMSO and THF. The compound is relatively stable under inert conditions but can react with reducing agents. It is not flammable and has a melting point around 190-195°C.

How is 2-Chloro-3,5-diiodopyridine (CAS: 856169-60-3) typically synthesized?

2-Chloro-3,5-diiodopyridine can be synthesized through the iodination of 2-chloropyridine using iodine in the presence of a Lewis acid catalyst such as aluminum trichloride (AlCl3). The reaction provides good yield and selectivity, making it a viable method for preparing this compound.

What industries use 2-Chloro-3,5-diiodopyridine (CAS: 856169-60-3)?

2-Chloro-3,5-diiodopyridine finds application in the pharmaceutical industry for the synthesis of certain intermediates and drug candidates. It is also used in the field of materials science, specifically in the development of sensors and semiconductors, due to its unique chemical properties.

What precautions should be taken when handling 2-Chloro-3,5-diiodopyridine (CAS: 856169-60-3)?

When handling 2-Chloro-3,5-diiodopyridine, it is essential to wear appropriate personal protective equipment (PPE) including gloves, lab coat, and goggles. Store the compound in a cool, dry place away from moisture and direct sunlight. Use a fume hood during handling to minimize inhalation risk. Always consult a safety data sheet (SDS) for detailed handling and emergency procedures.