1-{[Bis(4-fluorophenyl)(methyl)silyl]methyl}-1H-1,2,4-triazole

Basic Information

View in Editor

CAS Number

85509-19-9

Molecular Formula

C16H15F2N3Si

Molecular Weight

315.4 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

55°

Boiling Point

393 °C [760mmHg]

Density

1.17

Flash Point

192°C

Refractive Index

1.563

SMILES

View in Editor

C[Si](CN1N=CN=C1)(C2=CC=C(F)C=C2)C3=CC=C(F)C=C3

InChI

InChI=1S/C16H15F2N3Si/c1-22(12-21-11-19-10-20-21,15-6-2-13(17)3-7-15)16-8-4-14(18)5-9-16/h2-11H,12H2,1H3

InChIKey

FQKUGOMFVDPBIZ-UHFFFAOYSA-N

LogP

1.9884999999999997

Topological Polar Surface Area

30.71 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

333

Safety Information

View Safety Information

GHS Hazard Pictograms

H302

H351

H411

Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H351 Suspected of causing cancer
Carcinogenicity

H411 Toxic to aquatic life with long lasting effects
Hazardous to the aquatic environment, long-term hazard

Sensitiveness

对光敏感

Toxicity

LD50 in male, female rats (mg/kg): 1110, 674 orally; in rabbits >2000 dermally (Fort, Moberg)

Synonyms & References

English

Flusilazole
1-((bis(4-fluorophenyl)methylsilyl)methyl)-1h-1,2,4-triazole
BIS(4-FLUOROPHENYL)(METHYL)(1H-1,2,4-TRIAZOL-1-YLMETHYL)SILANE
CAPITAN
NUSTAR
NUSTAR(R)
OLYMP
OLYMP(R)
PUNCH
PUNCH(R)
SANCTION
dpx-h6573
flusilazol
Flusilazole solution
bis(4-fluorophenyl)-methyl-(1,2,4-triazol-1-ylmethyl)silane
1-[[bis(4-fluorophenyl)methylsilyl]methyl]-1H-1,2,4-triazole
1-{[bis(4-fluorophenyl)(methyl)silyl]methyl}-1H-1,2,4-triazole
Caswell No. 419K
Fluzilazol
Bis(4-fluorophenyl)methyl((1H-1,2,4-triazol-1-yl)methyl)silane
Flusiazole
DPX-H6573
1-((Bis(4-fluorophenyl)methylsilyl)methyl)-1H-1,2,4-triazole

MDL Number

MFCD01076615

Customs Code

2933990015

FAQ

What is 1-{[Bis(4-fluorophenyl)(methyl)silyl]methyl}-1H-1,2,4-triazole (CAS: 85509-19-9)?

1-{[Bis(4-fluorophenyl)(methyl)silyl]methyl}-1H-1,2,4-triazole is a synthetic organic compound with the CAS number 85509-19-9. It contains a triazole ring and a silyl group, making it a versatile intermediate in chemical synthesis. The compound is known for its stability and reactivity, often used in the development of pharmaceuticals and materials science applications.

What are the main uses of 1-{[Bis(4-fluorophenyl)(methyl)silyl]methyl}-1H-1,2,4-triazole (CAS: 85509-19-9)?

This compound is primarily used as an intermediate in the synthesis of pharmaceuticals, particularly in drug development targeting diseases such as cancer and neurological disorders. It also finds applications in polymer science and materials research due to its unique chemical structure and functional groups. Its use in industrial and research settings is supported by its chemical versatility and reactivity.

Is 1-{[Bis(4-fluorophenyl)(methyl)silyl]methyl}-1H-1,2,4-triazole (CAS: 85509-19-9) safe?

The safety of 1-{[Bis(4-fluorophenyl)(methyl)silyl]methyl}-1H-1,2,4-triazole depends on its handling and exposure conditions. It is generally considered safe when used in controlled laboratory environments, but standard safety precautions should be followed, such as wearing protective gloves and goggles. Proper ventilation and adherence to chemical safety guidelines are essential to ensure safe handling and minimize potential risks.

How should 1-{[Bis(4-fluorophenyl)(methyl)silyl]methyl}-1H-1,2,4-triazole (CAS: 85509-19-9) be stored?

This compound should be stored in a cool, dry, and dark place, ideally at temperatures below 25°C. It is sensitive to moisture and should be kept in a sealed container with a desiccant. Avoid exposure to air and direct light to maintain stability. Storage conditions should follow standard chemical safety and handling protocols to ensure product integrity and safety.