N-{(6S)-8-Fluoro-6-[(2S,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]-4-isopropyl-5,6-dihydrobenzo[h]quinazolin-2-yl}-N-methylmethanesulfonamide | CAS No. 854898-47-8

N-{(6S)-8-Fluoro-6-[(2S,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]-4-isopropyl-5,6-dihydrobenzo[h]quinazolin-2-yl}-N-methylmethanesulfonamide

Basic Information

CAS Number

854898-47-8

Molecular Formula

C22H26FN3O5S

Molecular Weight

463.53 g/mol

AD

Basic Physical Properties

CC(C)C1=NC(=NC2=C1CC(C3=C2C=CC(=C3)F)C4CC(CC(=O)O4)O)N(C)S(=O)(=O)C

InChI

InChI=1S/C22H26FN3O5S/c1-11(2)20-17-10-16(18-8-13(27)9-19(28)31-18)15-7-12(23)5-6-14(15)21(17)25-22(24-20)26(3)32(4,29)30/h5-7,11,13,16,18,27H,8-10H2,1-4H3/t13-,16+,18+/m1/s1

InChIKey

VLAHUUGOOLLUEH-SKDZVZGDSA-N

LogP

2.5081000000000007

Topological Polar Surface Area

109.69 Ų

Hydrogen Bond Donor/Acceptor

1 / 8

Synonyms & References

English

  • N-[(6S)-8-Fluoro-5,6-dihydro-4-(1-methylethyl)-6-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]benzo[h]quinazolin-2-yl]-N-methylmethanesulfonamide
  • N-[(6S)-8-Fluoro-5,6-dihydro-4-(1-methylethyl)-6-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]b
  • N-[(6S)-8-Fluoro-5,6-dihydro-4-(1-methylethyl)-6-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]benzo[h]quinazolin-2...

MDL Number

MFCD28358817

FAQ

What regulatory guidelines apply to N-{(6S)-8-Fluoro-6-[(2S,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]-4-isopropyl-5,6-dihydrobenzo[h]quinazolin-2-yl}-N-methylmethanesulfonamide (CAS: 854898-47-8)?

This compound falls under the jurisdiction of the GHS (Globally Harmonized System of Classification and Labeling of Chemicals) for classification and labeling. In the European Union, it is also subject to the REACH regulations. For use in the United States, FDA and EPA guidelines apply for safety and environmental concerns. Specific handling and storage guidelines per regulation should be consulted for proper management.

Are there alternatives to N-{(6S)-8-Fluoro-6-[(2S,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]-4-isopropyl-5,6-dihydrobenzo[h]quinazolin-2-yl}-N-methylmethanesulfonamide (CAS: 854898-47-8) in synthesis?

While specific alternatives may vary based on the desired outcome, similar functional groups such as fluoro or amide functionalities could be found in various alternatives. Commonly, reagents like methyl chloroformate or other amine derivatives could be considered as substitutes, but it is crucial to evaluate each alternative for its specific reactivity and compatibility.

What is the market or research trend for N-{(6S)-8-Fluoro-6-[(2S,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]-4-isopropyl-5,6-dihydrobenzo[h]quinazolin-2-yl}-N-methylmethanesulfonamide (CAS: 854898-47-8)?

The market and research trends for this compound are currently focused on its potential applications in medicinal chemistry and pharmaceuticals. There is a growing interest in developing new drugs and treatments, particularly in areas such as oncology and inflammation. Price trends are subject to supply and demand, but research into novel therapeutic agents is driving demand.

How should waste containing N-{(6S)-8-Fluoro-6-[(2S,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]-4-isopropyl-5,6-dihydrobenzo[h]quinazolin-2-yl}-N-methylmethanesulfonamide (CAS: 854898-47-8) be handled?

Waste containing this compound should be collected and stored in appropriate containers, ensuring proper labeling. For disposal, incineration or professional waste treatment facilities should be used. Environmental protection measures must include the use of personal protective equipment and adherence to local and international environmental regulations to prevent contamination and ensure safe disposal.

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